AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 M.
仅供研究使用。 我们不向患者出售。
| 名称 | AZD-3965 |
|---|---|
| Iupac 化学名称 | (S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione |
| 同义词 | AZD3965 ; AZD 3965 |
| 英文同义词 | AZD3965 ; AZD 3965 |
| 分子式 | C21H24F3N5O5S |
| 分子量 | 515.50597 |
| Smile | O=C1N(C(C)C)C2=C(C(C(N3OC[C@@](C)(O)C3)=O)=C(CC4=C(C(F)(F)F)NN=C4C)S2)C(N1C)=O |
| InChiKey | PRNXOFBDXNTIFG-FQEVSTJZSA-N |
| InChi | InChI=1S/C21H24F3N5O5S/c1-9(2)29-18-14(16(30)27(5)19(29)32)13(17(31)28-7-20(4,33)8-34-28)12(35-18)6-11-10(3)25-26-15(11)21(22,23)24/h9,33H,6-8H2,1-5H3,(H,25,26)/t20-/m0/s1 |
| Cas号 | 1448671-31-5 |
| 相关CAS号 | 1448671-31-5 |
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Off-white solid to white solid |
|---|---|
| 纯度 | 98% |
| 存储 | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| 可溶性 | Soluble in DMSO |
| 处理方式 | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| 运输条件 | Shipped under ambient temperature |
| 海关编码 | 2933599090 |
| Targets | selective MCT1 inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |