武汉永璨生物科技有限公司
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抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
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JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Microbiology
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分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
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Deuterated
Fluorides
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Indoles and Oxindoles
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 A
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产品名字索引 A
AMG 900
(Catalog# : 011803, Cas# :
945595-80-2
)
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/
APTO-253
(Catalog# : 011802, Cas# :
1422731-37-0
)
APTO-253 is a small molecule inhibitor of human metal-regulatory transcription factor
AC-55541
(Catalog# : 011302, Cas# :
916170-19-9
)
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist.
AZ 628
(Catalog# : 011120, Cas# :
878739-06-1
)
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM
AZD-5582
(Catalog# : 011117, Cas# :
1258392-53-8
)
AZD5582 is a potent IAP inhibitor, which is a dimeric compound based on the AVPI moti
Arbidol hydrochloride
(Catalog# : 011111, Cas# :
131707-23-8
)
Arbidol is an broad-spectrum antiviral chemical agent which can inhibit cell entry of
APY29
(Catalog# : 011108, Cas# :
1216665-49-4
)
APY29 is an allosteric modulator of IRE1; inhibits IRE1 autophosphorylation (IC50 = 2
AMG-47a
(Catalog# : 011107, Cas# :
882663-88-9
)
AMG-47a is a potent inhibitor of Lck and T cell proliferation.
ARQ-736
(Catalog# : 011104, Cas# :
1228237-57-7
)
ARQ 736 is a potent and selective BRAF inhibitor.
AZD4547
(Catalog# : 010820, Cas# :
1035270-39-3
)
AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2
AZD-1480
(Catalog# : 010816, Cas# :
935666-88-9
)
AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM, selectivity a
Avutometinib ( 别名: Ro 5126766; CH5126766 )
(Catalog# : 25152, Cas# :
946128-88-7
)
Avutometinib(别名:RO-5126766、CH-5126766)是一种正在开发的 Ras-Raf-ME
AZD8330
(Catalog# : 010809, Cas# :
869357-68-6
)
AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 n
AS703026
(Catalog# : 010808, Cas# :
1236699-92-5
)
AS703026 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2)
AZ505
(Catalog# : 010803, Cas# :
1035227-43-0
)
AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=
AG-L-59687
(Catalog# : 010428, Cas# :
793035-88-8
)
Coming soon!
AG1024
(Catalog# : 010422, Cas# :
65678-07-1
)
AG-1024 inhibits IGF-1R autophosphorylation with IC50 of 7 M, less potent to IR with
Almotriptan
(Catalog# : 010418, Cas# :
154323-57-6
)
Almotriptan is a 5-HT1B/1D-receptor agonist used to treat migraine.
AM630
(Catalog# : 010410, Cas# :
164178-33-0
)
AM630 is a selectivity CB2 antagonist with Ki of 31.2 nM; > 150 fold selectivity o
AZD-8055
(Catalog# : 123019, Cas# :
1009298-09-2
)
AZD-8055 is an inhibitor of the mammalian target of rapamycin (mTOR) with potential a
Amuvatinib
(Catalog# : 123016, Cas# :
850879-09-3
)
Amuvatinib is a potent and multi-targeted inhibitor of c-Kit, PDGFR and Flt3 with IC5
AR-42
(Catalog# : 123009, Cas# :
935881-37-1
)
AR-42 is a novel, oral cancer therapy currently in early clinical development.
A-966492
(Catalog# : 123006, Cas# :
934162-61-5
)
A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 n
AMG 487
(Catalog# : 122942, Cas# :
473719-41-4
)
AMG 487 is a small molecule antagonist of the chemokine receptor CXCR3.
Atosiban acetate
(Catalog# : 122931, Cas# :
90779-69-4
)
Atosiban is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/
AST-1306
(Catalog# : 122926, Cas# :
897383-62-9
)
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and
AZD8186
(Catalog# : 122925, Cas# :
1627494-13-6
)
AZD8186 is an isoform-specific small-molecule PI3K inhibitor, potently inhibits PI3K
AG-120
(Catalog# : 122906, Cas# :
1448346-63-1
)
AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), wi
AZD-5423
(Catalog# : 122902, Cas# :
1034148-04-3
)
Coming soon!
A 83-01
(Catalog# : 122843, Cas# :
909910-43-6
)
A 83-01 is a selective inhibitor of TGF- type I receptor ALK5 kinase, type I activin/
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Temozolomide
(Catalog# : 25209, Cas# :
85622-93-1
)
替莫唑胺是一种烷化剂。
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,
Opakalim
(Catalog# : 25193, Cas# :
2376397-93-0
)
Opakalim(BHV-7000)是Kv7.2/7.3钾通道(KCNQ2/3)的口服小分子激活剂,
PF-06835919 ( MDK-1846 )
(Catalog# : 193264, Cas# :
2102501-84-6
)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
MK256
(Catalog# : 25208, Cas# :
2271348-04-8
)
MK256是一种新型CDK8抑制剂,通过下调STAT通路在急性髓系白血病(
NSD1 抑制剂 BT5
(Catalog# : 25207, Cas# :
2351225-46-0
)
BT5可有效抑制NSD1,与细胞中的SET结构域结合,并降低H3K36me2水平。
MA242 TFA
(Catalog# : 25206, Cas# :
1049704-18-8
)
MA242是一种MDM2和NFAT1双重抑制剂,可诱导MDM2自泛素化及降解,并抑
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 )是一种口服选择性成纤维细胞生长因子受体3(
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B 是一种高效、选择性变构 M1 毒蕈碱和 σ1 受体激动剂。 AF710
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A抑制剂5具有抑制MAT2A的高效力和对MTAP缺失的癌症细胞系的显著