Selnoflast , also known as RO-7486967 or IZD334, is a potent small molecule that inhibits the NLRP3 inflammasome.
For research use only. We do not sell to patients.
Name | Selnoflast (Synonyms: RO-7486967 ; IZD334) |
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Iupac Chemical Name | 1-ethyl-N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]piperidine-4-sulfonamide |
Synonyms | Selnoflast ; RO-7486967 ; RO7486967 ; RO 7486967 ; IZD334 ; IZD-334 ; IZD 334 ; RG6418 ; RG- 6418 ; RG 6418 |
Molecular Formula | C20H29N3O3S |
Molecular Weight | 391.53 |
Smile | O=S(C1CCN(CC)CC1)(NC(NC2=C3CCCC3=CC4=C2CCC4)=O)=O |
InChiKey | OHIFQOUPTWBQLE-UHFFFAOYSA-N |
InChi | InChI=1S/C20H29N3O3S/c1-2-23-11-9-16(10-12-23)27(25,26)22-20(24)21-19-17-7-3-5-14(17)13-15-6-4-8-18(15)19/h13,16H,2-12H2,1H3,(H2,21,22,24) |
CAS Number | 2260969-36-4 |
Related CAS | 2260969-36-4 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | White to off-white (Solid) |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |