Saruparib
Catalog No: 24100
CAS Number: 2589531-76-8
Purity: 98% Min.
Saruparib, also known as AZD5305 is a potent, selective and oral active PARP inhibitor. AZD5305 is a highly potent inhibitor of PARP1, with significant PARP1-DNA trapping activity, no PARP2-activity, nor binding activity to any other members of the PARP family. AZD5305 has excellent secondary pharmacology and physicochemical properties as well as high oral bioavailability in preclinical species.
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Chemical Information
| Name | Saruparib |
|---|---|
| Iupac Chemical Name | 5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)piperazin-1-yl)-N-methylpicolinamide |
| Synonyms | AZD5305; AZD-5305; AZD 5305; Saruparib |
| Molecular Formula | C22H26N6O2 |
| Molecular Weight | 406.48 |
| Smile | O=C(C1=NC=C(N2CCN(CC3=CC(N4)=C(N=C3)C=C(CC)C4=O)CC2)C=C1)NC |
| InChiKey | WQAVGRAETZEADU-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H26N6O2/c1-3-16-11-19-20(26-21(16)29)10-15(12-24-19)14-27-6-8-28(9-7-27)17-4-5-18(25-13-17)22(30)23-2/h4-5,10-13H,3,6-9,14H2,1-2H3,(H,23,30)(H,26,29) |
| CAS Number | 2589531-76-8 |
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Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色固体 |
|---|---|
| Purity | 98% Min. |
| Storage | 0-4℃，可保存几天到几周；-20℃，可保存 几个月。 |
| Solubility | 溶于DMSO等有机溶剂 |
| Handling | |
| Shipping Condition | 可以在室温下进行运输。 |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
