Sevabertinib ( BAY-2927088 )
Catalog No: 25079
CAS Number: 2521285-05-0
Purity: ≧98.0%
Sevabertinib ( BAY-2927088 ) is a oral, non-covalent, tyrosine kinase receptor inhibitor (TKI) active against EGFR mutant forms with exon 19 deletions, exon 20 insertions and/or C797S resistance mutations.
For research use only. We do not sell to patients.
Chemical Information
| Name | Sevabertinib ( BAY-2927088 ) |
|---|---|
| Iupac Chemical Name | (S)-2-(3-((1,4-dioxan-2-yl)methoxy)pyridin-4-yl)-3-((3-chloro-2-methoxyphenyl)amino)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one |
| Synonyms | Sevabertinib ; BAY-2927088 ; BAY2927088 ; BAY 2927088 |
| Molecular Formula | C24H25ClN4O5 |
| Molecular Weight | 484.94 |
| Smile | O=C1C2=C(NC(C3=C(OC[C@H]4OCCOC4)C=NC=C3)=C2NC5=CC=CC(Cl)=C5OC)CCN1 |
| InChiKey | VYQVHWNNPKOJEA-AWEZNQCLSA-N |
| InChi | InChI=1S/C24H25ClN4O5/c1-31-23-16(25)3-2-4-18(23)29-22-20-17(6-8-27-24(20)30)28-21(22)15-5-7-26-11-19(15)34-13-14-12-32-9-10-33-14/h2-5,7,11,14,28-29H,6,8-10,12-13H2,1H3,(H,27,30)/t14-/m0/s1 |
| CAS Number | 2521285-05-0 |
| Related CAS | 2521285-05-0 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
