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PF-0684000

Catalog No.: 184318
Cas No.: 198474-05-4
Purity : >98%
184318 - PF-0684000 | CAS 198474-05-4

Catalog number : 184318

CAS number : 198474-05-4

Molecular Formula : C12H9FN2O2

Molecular Weight : 232.2144

Iupac Chemical Name : 3‑(5-Fluoro‑1H‑indol-3-yl)pyrrolidine-2,5-dione

Smile : O=C(C(C1=CNC2=C1C=C(F)C=C2)C3)NC3=O

InChiKey : MXKLDYKORJEOPR-UHFFFAOYSA-N

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SynonymsEOS200271, EOS-200271; EOS 200271; PF-0684000; PF 06840003; PF06840003.
Molecular FormulaC12H9FN2O2
Molecular Weight232.2144
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileO=C(C(C1=CNC2=C1C=C(F)C=C2)C3)NC3=O
InChiKeyMXKLDYKORJEOPR-UHFFFAOYSA-N
InChiInChI=1S/C12H9FN2O2/c13-6-1-2-10-7(3-6)9(5-14-10)8-4-11(16)15-12(8)17/h1-3,5,8,14H,4H2,(H,15,16,17)
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PF-0684000, also known as EOS200271, is potent IDO-1 inhibitor (IC50 0.15 μM). PF-0684000 has moderate hIDO1 enzyme inhibition (IC50 0.41 μM).

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