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PF-0684000

Catalog No.: 184318
Cas No.: 198474-05-4
Purity : >98%

PF-0684000, also known as EOS200271, is potent IDO-1 inhibitor (IC50 0.15 μM). PF-0684000 has moderate hIDO1 enzyme inhibition (IC50 0.41 μM).

For research use only. We do not sell to patients.

Chemical Information

NamePF-0684000
Iupac Chemical Name3‑(5-Fluoro‑1H‑indol-3-yl)pyrrolidine-2,5-dione
SynonymsEOS200271, EOS-200271; EOS 200271; PF-0684000; PF 06840003; PF06840003.
Molecular FormulaC12H9FN2O2
Molecular Weight232.2144
SmileO=C(C(C1=CNC2=C1C=C(F)C=C2)C3)NC3=O
InChiKeyMXKLDYKORJEOPR-UHFFFAOYSA-N
InChiInChI=1S/C12H9FN2O2/c13-6-1-2-10-7(3-6)9(5-14-10)8-4-11(16)15-12(8)17/h1-3,5,8,14H,4H2,(H,15,16,17)
CAS Number198474-05-4
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

184318 - PF-0684000 | CAS 198474-05-4

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