PF-0684000, also known as EOS200271, is potent IDO-1 inhibitor (IC50 0.15 μM). PF-0684000 has moderate hIDO1 enzyme inhibition (IC50 0.41 μM).
For research use only. We do not sell to patients.
| Name | PF-0684000 |
|---|---|
| Iupac Chemical Name | 3‑(5-Fluoro‑1H‑indol-3-yl)pyrrolidine-2,5-dione |
| Synonyms | EOS200271, EOS-200271; EOS 200271; PF-0684000; PF 06840003; PF06840003. |
| Molecular Formula | C12H9FN2O2 |
| Molecular Weight | 232.2144 |
| Smile | O=C(C(C1=CNC2=C1C=C(F)C=C2)C3)NC3=O |
| InChiKey | MXKLDYKORJEOPR-UHFFFAOYSA-N |
| InChi | InChI=1S/C12H9FN2O2/c13-6-1-2-10-7(3-6)9(5-14-10)8-4-11(16)15-12(8)17/h1-3,5,8,14H,4H2,(H,15,16,17) |
| CAS Number | 198474-05-4 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |