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PRN-1371

Catalog No.: 17101614
Cas No.: 1802929-43-6
Purity : >98%
17101614 - PRN-1371 | CAS 1802929-43-6

Catalog number : 17101614

CAS number : 1802929-43-6

Molecular Formula : C26H30Cl2N6O4

Molecular Weight : 561.464

Chemical Name : PRN-1371

Smile : CNC1=NC=C2C(N(CCCN3CCN(C(C=C)=O)CC3)C(C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)=C2)=O)=N1

InChiKey : PUIXMSRTTHLNKI-UHFFFAOYSA-N

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SynonymsPRN-1371; PRN1371; PRN 1371.
Molecular FormulaC26H30Cl2N6O4
Molecular Weight561.464
Appearanceo
Purity>98%
SolubilitySoluble in DMSO, not in water
Storage3 years -20ºCpowder
Shipping ConditionShipped under ambient temperature
SmileCNC1=NC=C2C(N(CCCN3CCN(C(C=C)=O)CC3)C(C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)=C2)=O)=N1
InChiKeyPUIXMSRTTHLNKI-UHFFFAOYSA-N
InChiInChI=1S/C26H30Cl2N6O4/c1-5-20(35)33-11-9-32(10-12-33)7-6-8-34-24-16(15-30-26(29-2)31-24)13-17(25(34)36)21-22(27)18(37-3)14-19(38-4)23(21)28/h5,13-15H,1,6-12H2,2-4H3,(H,29,30,31)
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PRN-1371 is a covalent, irreversible, highly selective FGFR1, 2, 3 and 4 inhibitor. PRN1371 inhibits all four FGFR isoforms and blocks aberrant FGFR kinase signaling.

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