PCI-29732是BTK抑制剂。它通过阻断B细胞抗原受体(BCR)介导的CD20+ B细胞中的基因表达。
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Name | PCI-29732 |
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Iupac Chemical Name | 1-Cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Synonyms | PCI-29732; PCI 29732; PCI29732; |
Molecular Formula | C22H21N5O |
Molecular Weight | 371.44 |
Smile | NC1=C2C(N(C3CCCC3)N=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1 |
InChiKey | GMJUPMONHWAZCP-UHFFFAOYSA-N |
InChi | InChI=1S/C22H21N5O/c23-21-19-20(26-27(16-6-4-5-7-16)22(19)25-14-24-21)15-10-12-18(13-11-15)28-17-8-2-1-3-9-17/h1-3,8-14,16H,4-7H2,(H2,23,24,25) |
CAS Number | 330786-25-9 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | 类白色至白色固体 |
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Purity | >98% |
Storage | 短期可在0-4度保存,数天至数月;长期可在-20度保存三年。 |
Solubility | 可溶于DMSO |
Handling | |
Shipping Condition | 可在常温下运输 |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |