Nizubaglustat (AZ-3102) is an oral small molecule which inhibits glucosylceramide synthase (GCS) and non-lysosomal glucosylceramidase (GbA2) .
For research use only. We do not sell to patients.
| Name | Nizubaglustat ( Synonyms: AZ-3102 ) |
|---|---|
| Iupac Chemical Name | (2S,3R,4R,5S)-1-[5-[(2-Fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol |
| Synonyms | Nizubaglustat ; AZ-3102 ; AZ 3102 ; AZ3102 |
| Molecular Formula | C24H32FNO5 |
| Molecular Weight | 433.52 |
| Smile | O[C@@H]1[C@H](CO)N(CCCCCOCC2=CC=C(C3=CC=CC=C3)C(F)=C2)C[C@H](O)[C@H]1O |
| InChiKey | IRIRASPSMMWZOM-CJRSTVEYSA-N |
| InChi | InChI=1S/C24H32FNO5/c25-20-13-17(9-10-19(20)18-7-3-1-4-8-18)16-31-12-6-2-5-11-26-14-22(28)24(30)23(29)21(26)15-27/h1,3-4,7-10,13,21-24,27-30H,2,5-6,11-12,14-16H2/t21-,22-,23+,24+/m0/s1 |
| CAS Number | 1633666-49-5 |
| Related CAS | 1633666-49-5 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |