Navacaprant ( BTRX-335140 )
Catalog No: 23122601
CAS Number: 2244614-14-8
Purity: ≧98.0%
Navacaprant (NMRA-335140, BTRX-140) is an oral, selective, reversible, small-molecule antagonist of the kappa opioid receptor (KOR) for the treatment of major depressive disorder.
For research use only. We do not sell to patients.
Chemical Information
| Name | Navacaprant ( BTRX-335140 ) |
|---|---|
| Iupac Chemical Name | 1-(6-ethyl-8-fluoro-4-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)piperidin-4 amine |
| Synonyms | BTRX-335140 ; BTRX 335140 ; BTRX335140 ; CYM-53093 ; CYM 53093 ; CYM53093 ; Navacaprant |
| Molecular Formula | C25H32FN5O2 |
| Molecular Weight | 453.56 |
| Smile | CCC1=CC(F)=C2C(C(C)=C(C3=NC(C)=NO3)C(N4CCC(NC5CCOCC5)CC4)=N2)=C1 |
| InChiKey | CQOJHAJWCDJEAT-UHFFFAOYSA-N |
| InChi | InChI=1S/C25H32FN5O2/c1-4-17-13-20-15(2)22(25-27-16(3)30-33-25)24(29-23(20)21(26)14-17)31-9-5-18(6-10-31)28-19-7-11-32-12-8-19/h13-14,18-19,28H,4-12H2,1-3H3 |
| CAS Number | 2244614-14-8 |
| Related CAS | 2244614-14-8 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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