NEO-811
Catalog No: 26A030
CAS Number: 3084635-78-6
Purity: ≧98.0%
NEO-811 is an investigational molecular glue degrader designed to induce targeted degradation of a key disease-driving protein and fully block a central signalling pathway implicated in ccRCC.
For research use only. We do not sell to patients.
Chemical Information
| Name | NEO-811 |
|---|---|
| Iupac Chemical Name | 3-(6-((R)-1-(4-(1,2,4-oxadiazol-3-yl)benzyl)-4-hydroxy-3,3-dimethylpiperidin-4-yl)-5-fluoroquinolin-3-yl)piperidine-2,6-dione hydrochloride |
| Synonyms | NEO-811 ; NEO 811 ; NEO811 ; NEO-811.HCl ; NEO 811.HCl ; NEO811.HCl ; |
| Molecular Formula | C30H31ClFN5O4 |
| Molecular Weight | 580.06 |
| Smile | O=C(C(C1=CC2=C(F)C([C@]3(O)C(C)(C)CN(CC4=CC=C(C5=NOC=N5)C=C4)CC3)=CC=C2N=C1)CC6)NC6=O.[H]Cl |
| InChiKey | QUOKMYXBBCWAFN-VYXIRICJSA-N |
| InChi | InChI=1S/C30H30FN5O4.ClH/c1-29(2)16-36(15-18-3-5-19(6-4-18)27-33-17-40-35-27)12-11-30(29,39)23-8-9-24-22(26(23)31)13-20(14-32-24)21-7-10-25(37)34-28(21)38;/h3-6,8-9,13-14,17,21,39H,7,10-12,15-16H2,1-2H3,(H,34,37,38);1H/t21?,30-;/m0./s1 |
| CAS Number | 3084635-78-6 |
| Related CAS | 3084635-78-6 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
