Nedisertib ( peposertib )
Catalog No: 25094
CAS Number: 1637542-33-6
Purity: ≧98.0%
Nedisertib, also known as M-3814, MSC2490484A, is an orally available inhibitor of DNA-dependent protein kinase (DNA-PK), with potential antineoplastic and chemo/radiosensitizing activities.
For research use only. We do not sell to patients.
Chemical Information
| Name | Nedisertib ( peposertib ) |
|---|---|
| Iupac Chemical Name | (S)-(2-chloro-4-fluoro-5-(7-morpholinoquinazolin-4-yl)phenyl)(6-methoxypyridazin-3-yl)methanol |
| Synonyms | MSC2490484A; MSC-2490484A; MSC 2490484A; M3814; M-3814; M 3814; nedisertib; peposertib, |
| Molecular Formula | C24H21ClFN5O3 |
| Molecular Weight | 481.91 |
| Smile | COC1=CC=C([C@@H](O)C2=CC(C3=C(C=CC(N4CCOCC4)=C5)C5=NC=N3)=C(F)C=C2Cl)N=N1 |
| InChiKey | MOWXJLUYGFNTAL-DEOSSOPVSA-N |
| InChi | InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3/t24-/m0/s1 |
| CAS Number | 1637542-33-6 |
| Related CAS | 1637542-33-6 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Light yellow to yellow (Solid) |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | DNA-PK Inhibitor |
|---|---|
| Mechanism | Nedisertib is an orally available inhibitor of DNA-dependent protein kinase (DNA-PK), with potential antineoplastic and chemo/radiosensitizing activities. |
| Cell study | |
| Animal study | |
| Clinical study | Clinical Phase II |
Not available
Chemical Structure
