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Inhibitors & Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Iodos
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
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Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
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Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
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Pyridines
Pyrimidines
Quinolines
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Name Index N
Nampt-IN-1
(Catalog# : 17022705, Cas# :
1698878-14-6
)
Nampt-IN-1 is a novel inhibitor of NAMPT with IC50 of 18 nM (NCI-H1155 cell), 49 nM (
NSC12
(Catalog# : 17021317, Cas# :
102586-30-1
)
NSC12 is an orally available pan-FGF trap able to inhibit FGF2/FGFR interaction and
NS-398 (NS398)
(Catalog# : 17011106, Cas# :
123653-11-2
)
NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for hum
Netarsudil (AR-13324) 2HCl
(Catalog# : 1710901, Cas# :
1253952-02-1
)
Netarsudil (a.k.a. AR-13324) is ROCK inhibitor with Ki value of 0.2-10.3 nM. It is cu
Naftifine
(Catalog# : 16122834, Cas# :
65472-88-0
)
Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis,
Nafamostat mesylate
(Catalog# : 16122833, Cas# :
82956-11-4
)
Nafamostat, also known as FUT-175, is a serine protease inhibitor and an anticoagulan
NSC697923
(Catalog# : 16122791, Cas# :
343351-67-7
)
NSC697923 is a cell-permeable and selective inhibitor of the Ub-conjugating enzyme (E
NVP-CGM097
(Catalog# : 16122789, Cas# :
1313363-54-0
)
NVP-CGM097 is a highly potent and selective MDM2 inhibitor. It binds to the p53 bindi
NSC228155
(Catalog# : 16122779, Cas# :
113104-25-9
)
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and mo
NQDI-1
(Catalog# : 16122772, Cas# :
175026-96-7
)
NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute
Nitroxoline
(Catalog# : 16122719, Cas# :
4008-48-4
)
Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive
Napabucasin
(Catalog# : 16122708, Cas# :
83280-65-3
)
Napabucasin is an orally available Stat3 and cancer cell stemness inhibitor.Napabucas
Necrosulfonamide
(Catalog# : 6111508, Cas# :
1360614-48-7
)
Necrosulfonamide is a very specific and potent necrosis inhibitor and blocks mixed li
Necrostatin 2 S enantiomer
(Catalog# : 6111412, Cas# :
852391-20-9
)
Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.Necrostatin 2 is a
Necrostatin 2 racemate
(Catalog# : 6111411, Cas# :
852391-15-2
)
Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.Necrostatin 2 is a
NBI-74330
(Catalog# : 6111112, Cas# :
855527-92-3
)
NBI-74330 is a small molecule antagonist for CXCR3, NBI-74330 demonstrates potent inh
Nastorazepide
(Catalog# : 6111110, Cas# :
209219-38-5
)
Nastorazepide (Z-360) is a selective, orally available, 1,5-benzodiazepine-derivative
NU6300
(Catalog# : 611923, Cas# :
2070015-09-5
)
NU6300 is a non-covalent ATP-competitive CDK2 inhibitor (IC50 = 0.16 mM). NU6300
NU 7026
(Catalog# : 6118017, Cas# :
154447-35-5
)
NU 7026 is a novel and potential inhibitor of the DNA repair enzyme DNA-dependent pro
NMS-859
(Catalog# : 161014001, Cas# :
1449236-96-7
)
NMS-859 is a potent and specific small molecule covalent inhibitor of the ATPase VCP/
NCT-501
(Catalog# : 16071414, Cas# :
1802088-50-1
)
NCT-501 is a potent ALDH1A1 inhibitor. Aldehyde dehydrogenases (ALDHs) metabolize rea
Naquotinib
(Catalog# : 16071107, Cas# :
448232-80-1
)
Naquotinib, also known as ASP8273, is an orally available, irreversible, third-genera
Necrostatin 2
(Catalog# : 16070914, Cas# :
852391-19-6
)
Necrostatin 2
Navitoclax (ABT-263)
(Catalog# : 16070102, Cas# :
923564-51-6
)
Navitoclax, also known as ABT-263, is an orally bioavailable, synthetic small-molecul
NSC5844
(Catalog# : 16060601, Cas# :
140926-75-6
)
NSC5844
NU2058
(Catalog# : 032515, Cas# :
161058-83-9
)
Coming soon!
NIBR189
(Catalog# : 012007, Cas# :
1599432-08-2
)
NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2
NS6180
(Catalog# : 011118, Cas# :
353262-04-1
)
NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents
NVP-ACC-789
(Catalog# : 010432, Cas# :
300842-64-2
)
Coming soon!
NVP-TNKS656
(Catalog# : 010408, Cas# :
1419949-20-4
)
NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC5
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-
Atuzabrutinib
(Catalog# : 25145, Cas# :
1581714-49-9
)
Atuzabrutinib, also known as PRN 473, is a Bruton's tyrosine kinase inhibitor.
Andamertinib
(Catalog# : 25144, Cas# :
2254145-43-0
)
Andamertinib is an epidermal growth factor receptor tyrosine kinase inhibitor. It is
MEN-1703
(Catalog# : 25143, Cas# :
2769008-22-0
)