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MAPK
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Metabolic Enzyme/Protease
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index N
N,N-DIETHYL-2,6-CIS-DIMETHYLPIPERIDINIUM IODIDE
(Catalog# : G20383, Cas# :
1335241-44-5
)
Navoximod free base
(Catalog# : 20290, Cas# :
1402837-78-8 (free base)
)
NE 52-QQ57
(Catalog# : 21233, Cas# :
1401728-56-0
)
NE52-QQ57 is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 si
NVS-PAK1-1
(Catalog# : 21231, Cas# :
1783816-74-9
)
NVS-PAK1-1 is a a specific allosteric PAK1 inhibitor.
Niraparib tosylate hydrate
(Catalog# : 2021115, Cas# :
1613220-15-7
)
Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PAR
N-(8-Benzyl-8-azabicyclo[3.2.1]oct-3-yl-exo)-2-methylpropanamide
(Catalog# : 2071632, Cas# :
376348-67-3
)
NCC007
(Catalog# : 2071529)
NCC007 is a novel CKIα and CKIδ dual inhibitor. NCC007 that showed stronger period
N-tert-butyl-3-[(2-chloro-5-methylpyrimidin-4-yl)amino]benzenesulfonamide
(Catalog# : 2062304, Cas# :
936092-53-4
)
N,N-dibenzyl-6-chloro-5-nitropyrimidine-4-amine
(Catalog# : 2062033, Cas# :
882272-97-1
)
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
(Catalog# : 2062032, Cas# :
1346133-39-8
)
N-(2-methylbenzyl)-4,5-dihydro-1H-imidazol-2-amine
(Catalog# : 2062031, Cas# :
38941-29-6
)
5-(N-PHTHALIMIDO)-2-PENTANONE
(Catalog# : 2062010, Cas# :
3197-25-9
)
N-Fmoc-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-L-serine
(Catalog# : 2061601, Cas# :
120173-57-1
)
NTP42
(Catalog# : 2051509, Cas# :
2055599-51-2
)
NTP42 is a novel antagonist of the thromboxane prostanoid receptor (TP), currently in
N-tert-butyloxycarbonyl-pyrrole
(Catalog# : S-204153, Cas# :
5176-27-2
)
N-(4-PENTYNYL)PHTHALIMIDE 97
(Catalog# : S-204150, Cas# :
6097-07-0
)
N-benzyl-2,4-dichloropyrimidine-5-carboxamide
(Catalog# : 197101, Cas# :
1019115-13-9
)
NVS-ZP7-4
(Catalog# : 204506, Cas# :
2349367-89-9 (free base)
)
NVS-ZP7-4 is a potent ZIP7 Inhibitor, which inhibits Notch signaling with IC50 of 0.1
NVP-2
(Catalog# : 193205, Cas# :
1263373-43-8
)
NVP-2 is an inhibitor of the cyclin-dependent kinase, CDK9.
NS-1652
(Catalog# : 19361, Cas# :
1566-81-0
)
NS-1652 is an anion conductance inhibitor.
NCT-506
(Catalog# : 19354, Cas# :
2231098-99-8
)
NCT-506 is an orally bioavailable aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors wit
Nelotanserin
(Catalog# : 191121, Cas# :
839713-36-9
)
Nelotanserin(APD125) is a potent and selective human 5-hydroxytryptamine2A inverse ag
ND-646
(Catalog# : 191102, Cas# :
1434639-57-2
)
ND-646 is-an allosteric inhibitor of the ACC enzymes ACC1 and ACC2 that prevents ACC
ND-630
(Catalog# : 19133, Cas# :
1434635-54-7
)
ND-630, also known as GS-0976, NDI-010976, and firsocostat, is a potent ACC inhibitor.
Naquotinib free base
(Catalog# : 1812297, Cas# :
1448232-80-1
)
Naquotinib, also known as ASP8273, is an orally available, irreversible, third-genera
N6022
(Catalog# : 1811304, Cas# :
1208315-24-5
)
N6022 is a potent, selective, reversible, and efficacious S-nitrosoglutathione reduct
Nexinhib20
(Catalog# : 1811152, Cas# :
331949-35-0
)
Nexinhib20 is a Rab27 inhibitor that inhibits neutrophil exocytosis and is active in
NGI-1
(Catalog# : 181171, Cas# :
790702-57-7
)
NGI-1, also knowns ML414, is a a cell-permeable inhibitor of oligosaccharyltransferas
NMS-E973
(Catalog# : 1810293, Cas# :
1253584-84-7
)
NMS-E973 is a novel, selective and potent inhibitor of heat shock protein 90 (Hsp90).
NCT-505
(Catalog# : 1810261, Cas# :
2231079-74-4
)
NCT-505 is an Orally Bioavailable aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitor with
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
DPTX-3186
(Catalog# : 26A010, Cas# :
3118994-80-9
)
DPTX3186, an orally administered small molecule condensate modulator (c-mod) inhibiti
Avasopasem manganese (GC-4419; M-40419)
(Catalog# : 25108, Cas# :
435327-40-5
)
Avasopasem manganese, also known as GC-4419; M 40419 and SC-72325A, is amimetic of th
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Kartogenin ( KGN )
(Catalog# : 52215, Cas# :
4727-31-5
)
Kartogenin (KGN) is a synthetic small molecule that stimulates chondrogenic cellular
Imisopasem manganese ( M40403; GC4403 )
(Catalog# : 72602, Cas# :
218791-21-0
)
Imisopasem manganese ( M40403; GC4403 ) is a stable non-peptidyl mimetic of MnSOD tha
Apecotrep (BI 764198)
(Catalog# : 26A048, Cas# :
2311863-36-0
)
Apecotrep (BI 764198) is a potential first-in-class, oral, selective TRPC6 inhibitor.
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2 is a pantothenate kinase inhibitor with IC50 values of 92 nM
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643 is a novel, orally available, non-covalent, macrocyclic, mutant selective OM
Gridegalutamide
(Catalog# : 26A044, Cas# :
2446929-86-6
)
gridegalutamide is an orally bioavailable androgen receptor (AR) degrader, with poten
BMS-986365 (Synonyms: CC-94676 )
(Catalog# : 25138, Cas# :
2446928-30-7
)
BMS-986365, also known as CC-94676, is an orally bioavailable androgen receptor (AR)