Nomelcitinib (D-2570) is a novel TYK2 allosteric inhibitor.
For research use only. We do not sell to patients.
| Name | Nomelcitinib ( D-2570 ) |
|---|---|
| Iupac Chemical Name | 4-((5-chloro-3-(methylsulfonyl)pyridin-2-yl)amino)-6-(cyclopropanecarboxamido)-N-(methyl-d3)pyridazine-3-carboxamide |
| Synonyms | D-2570 ; D 2570 ; D2570 |
| Molecular Formula | C16H14D3ClN6O4S |
| Molecular Weight | 427.1 |
| Smile | O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=NC=C(Cl)C=C3S(=O)(C)=O)NC([2H])([2H])[2H] |
| InChiKey | QZZGWCBTIULDRA-FIBGUPNXSA-N |
| InChi | InChI=1S/C16H17ClN6O4S/c1-18-16(25)13-10(6-12(22-23-13)21-15(24)8-3-4-8)20-14-11(28(2,26)27)5-9(17)7-19-14/h5-8H,3-4H2,1-2H3,(H,18,25)(H2,19,20,21,22,24)/i1D3 |
| CAS Number | 2794195-73-4 |
| Related CAS | 2794195-73-4 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |