NSC-92828
NSC-92828, also known as 3-Phenanthrenebutyric acid, is a Protein–protein interaction inhibitor (2P2 inhibitor or 2P2I). Protein–protein recognition is the cornerstone of multiple cellular and pathological functions. Therefore, protein–protein interaction inhibition (2P2I) is endowed with great therapeutic potential despite the initial belief that 2P2I was refractory to small-molecule intervention.
For research use only. We do not sell to patients.
Chemical Information
| Name | NSC-92828 |
|---|---|
| Iupac Chemical Name | 3-Phenanthrenebutyric acid |
| Synonyms | NSC-92828; NSC 92828; NSC92828; 3-Phenanthrenebutyric acid; |
| Molecular Formula | C18H16O2 |
| Molecular Weight | 264.32 |
| Smile | O=C(O)CCCC1=CC=C2C=CC3=CC=CC=C3C2=C1 |
| InChiKey | NYIVWTWKIQOBKO-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H16O2/c19-18(20)7-3-4-13-8-9-15-11-10-14-5-1-2-6-16(14)17(15)12-13/h1-2,5-6,8-12H,3-4,7H2,(H,19,20) |
| CAS Number | 13728-56-8 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Betzi S, Restouin A, Opi S, Arold ST, Parrot I, Guerlesquin F, Morelli X, Collette Y. Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19256-61. doi: 10.1073/pnas.0707130104. Epub 2007 Nov 27. PMID: 18042718; PMCID: PMC2148277.
Chemical Structure
