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MAPK
Membrane Transporter/Ion Channel
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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TGF-beta/Smad
Ubiquitin
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Cas Index 1
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Cas Index 1
1254036-71-9 | GSK2269557 free base
(Catalog# : 611826)
GSK-2269557 (free base) is a potent and selective PI3Kδ inhibitor over the closely r
1047635-80-2 | GSK2141795 (hydrochloride)
(Catalog# : 611807)
GSK2141795 Hcl is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM
1432913-36-4 | GX-674
(Catalog# : 1681201)
GX-674 is an aryl sulfonamide class of antagonists that inhibits Nav1.7.Nav (voltage-
1382979-44-3 | GDC-0084
(Catalog# : 16071405)
GDC-0084, also known as RG7666, is a phosphatidylinositol 3-kinase (PI3K) inhibitor w
1254053-43-4 | Gilteritinib
(Catalog# : 16071108)
Gilteritinib, also known as (ASP2215, is a potent FLT3/AXL inhibitor, which showed po
186452-09-5 | GPI-1046
(Catalog# : 16071027)
GPI-1046
1346607-05-3 | GSK621
(Catalog# : 16070905)
GSK621 is a specific and potentAMPKactivator.
1300031-49-5 | GSK1210151A
(Catalog# : 16070808)
GSK1210151A, also known as I-BET151, is a BET bromodomain inhibitor, which blocks rec
1453848-26-4 | GDC-0994
(Catalog# : 16062801)
GDC-0994, also known as RG7842, is an orally available inhibitor of extracellular sig
117928-94-6 | GLYX 13
(Catalog# : 011809)
Coming soon!
1168091-68-6 | GDC-0623
(Catalog# : 010811)
GDC-0623 is a potent, ATP-uncompetitive inhibitors of MEK1(Ki=0.13 nM, +ATP); 6-fold
1075236-89-3 | Gepotidacin
(Catalog# : 010610)
Gepotidacin is a potent Type II DNA topoisomerase inhibitor. Gepotidacin is a novel a
1217457-86-7 | GGTI-298
(Catalog# : 010609)
GGTI-298 is a potent geranylgeranyltransferase-I (GGTase-I) inhibitor with potential
1443461-21-9 | GSK2838232
(Catalog# : 122924)
GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed f
1431368-48-7 | GSK-LSD1 2HCl
(Catalog# : 122505)
Coming soon!
1346704-33-3 | GSK343
(Catalog# : 122402)
GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM, showing 60 fold se
1032823-75-8 | GSK1292263
(Catalog# : 121430)
GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabet
1089283-49-7 | GSK1904529A
(Catalog# : 121428)
GSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM, &
1229236-86-5 | Gandotinib(LY2784544)
(Catalog# : 91415)
Gandotinib is an orally bioavailable imidazopyridazine and inhibitor of Janus kinase
1365888-06-7 | GDC-0810 ( Brilanestrant , ARN-810 )
(Catalog# : 90731)
GDC-0810 (Brilanestrant, ARN-810, RG6046) is a selective estrogen receptor degrader (
1380672-07-0 | G007-LK
(Catalog# : 62908)
G007-LK is specific tankyrase 1/2 inhibitor.G007-LK (66) displayed high selectivity t
1207360-89-1 | GDC-0349
(Catalog# : 62702)
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR.
103766-25-2 | Gimeracil
(Catalog# : 52804)
Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which
1260907-17-2 | GSK 525762A
(Catalog# : 52745)
GSK 525762A (I-BET 762) is an inhibitor for BET proteins with IC50 of ~35 nM.
1218942-37-0 | GKT137831
(Catalog# : 52627)
GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 14040 nM and 11
1372540-25-4 | GSK2636771
(Catalog# : 52618)
GSK2636771 is a potent, orally bioavailable and selective inhibitor of PI3K (0.89 nM)
1047634-63-8 | GSK2110183
(Catalog# : 52584)
GSK2110183 is an orally bioavailable, selective, ATP-competitive and potent pan-Akt i
1262618-39-2 | GS967
(Catalog# : 52216)
GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late
1346574-57-9 | GSK126
(Catalog# : 52208)
GSK126 is a potent, highly selectiveEZH2 methyltransferaseinhibitor withIC50of 9.9 nM
1346572-63-1 | GSK503
(Catalog# : 51805)
GSK-503 is a potent EZH2 inhibitor with potential anticancer activity. Reference: 1.
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
85622-93-1 | Temozolomide
(Catalog# : 25209)
Temozolomide is an alkylating agent.
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
2376397-93-0 | Opakalim
(Catalog# : 25193)
Opakalim (BHV-7000) is an oral, small-molecule activator of Kv7.2/7.3 potassium chann
2102501-84-6 | PF-06835919 ( MDK-1846 )
(Catalog# : 193264)
MDK1846 is a potent ketohexokinase (KHK) inhibitor.
2271348-04-8 | MK256
(Catalog# : 25208)
MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downreg
2351225-46-0 | NSD1 inhibitor BT5
(Catalog# : 25207)
BT5 potently inhibits NSD1, engages the SET domain in cells, and reduces H3K36me2 lev
1049704-18-8 | MA242 TFA
(Catalog# : 25206)
MA242 isMDM2 and NFAT1 dual inhibitorthat induces MDM2 auto-ubiquitination and degrad
2800223-30-5 | Dabogratinib ( TYRA-300 )
(Catalog# : 24073)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
N/A | AF710B
(Catalog# : 25205)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
2957874-18-7 | MAT2A inhibitor 5
(Catalog# : 25204)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit