Linafexor (Synonyms: CS-0159) is a potent non-bile-acid agonist of the farnesoid X receptor (FXR).
For research use only. We do not sell to patients.
| Name | Linafexor (Synonyms: CS-0159) |
|---|---|
| Iupac Chemical Name | 3-(4-((1R,3r,5S)-3-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)-2-fluorophenyl)-1,2,4-oxadiazol-5(4H)-one |
| Synonyms | Linafexor; CS-0159; CS 0159; CS0159 |
| Molecular Formula | C28H25Cl2FN4O4 |
| Molecular Weight | 571.43 |
| Smile | ClC1=C(C2=NOC(C3CC3)=C2CO[C@@H]4C[C@]5(N([C@@]([H])(C4)CC5)C6=CC(F)=C(C=C6)C7=NOC(N7)=O)[H])C(Cl)=CC=C1 |
| InChiKey | CEEANZUSISGCJL-VQFNDLOPSA-N |
| InChi | InChI=1S/C28H25Cl2FN4O4/c29-21-2-1-3-22(30)24(21)25-20(26(38-33-25)14-4-5-14)13-37-18-10-15-6-7-16(11-18)35(15)17-8-9-19(23(31)12-17)27-32-28(36)39-34-27/h1-3,8-9,12,14-16,18H,4-7,10-11,13H2,(H,32,34,36)/t15-,16+,18+ |
| CAS Number | 2765593-43-7 |
| Related CAS | 2765593-43-7 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | IDH1 inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |