GSK1210151A
Catalog No: 16070808
CAS Number: 1300031-49-5
Purity: 98% by HPLC
GSK1210151A, also known as I-BET151, is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. I-BET151 ( GSK1210151A ) shows good oral bioavailability in both the rat and minipig as well as demonstrating efficient suppression of bacterial induced inflammation and sepsis in a murine in vivo endotoxaemia model.
For research use only. We do not sell to patients.
Chemical Information
| Name | GSK1210151A |
|---|---|
| Iupac Chemical Name | 7-(3,5-dimethylisoxazol-4-yl)-8-methoxy-1-((R)-1-(pyridin-2-yl)ethyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one |
| Synonyms | IBET151; IBET-151; |
| Molecular Formula | C23H21N5O3 |
| Molecular Weight | 415.44 |
| Smile | CC1=NOC(=C1C=1C(=CC=2C3=C(C=NC2C1)NC(N3[C@H](C)C3=NC=CC=C3)=O)OC)C |
| InChiKey | VUVUVNZRUGEAHB-CYBMUJFWSA-N |
| InChi | InChI=1S/C23H21N5O3/c1-12-21(14(3)31-27-12)16-9-18-15(10-20(16)30-4)22-19(11-25-18)26-23(29)28(22)13(2)17-7-5-6-8-24-17/h5-11,13H,1-4H3,(H,26,29)/t13-/m1/s1 |
| CAS Number | 1300031-49-5 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
