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MAPK
Membrane Transporter/Ion Channel
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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Cas Index 1
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Cas Index 1
1258292-64-6 | GDC-046
(Catalog# : L20342)
GDC-046 is a potent, selective, and orally bioavailable TYK2 inhibitor for TYK2, JAK1
1831144-46-7 | GDC-0214
(Catalog# : c20341)
iJak-381 is a highly potent, selective, and inhalable Janus kinase-1 (JAK-1) inhibito
106740-09-4 | GYY4137
(Catalog# : L20339)
GYY4137 is a novel water-soluble and slow releasing H2S donor. Hydrogen sulfide (H2S)
1139889-93-2 | Golgicide A
(Catalog# : 20292)
Golgicide A is a Potent, selective and reversible inhibitor of GBF1 ArfGEF. Golgicide
113852-41-8 | GS 0573 ( PMEDAP )
(Catalog# : 20275)
GS 0573 is an antiviral compound that has been studied for potential treatment of Fel
1953133-47-5 | Giredestrant
(Catalog# : 21248)
Giredestrant, also known as GDC-9545 and RG6171, is a SERD. GDC-9545 is an orally ava
1652591-81-5 | GSK484 HCl
(Catalog# : 20111801)
GSK484 is a potent PAD-4 inhibitor (Protein-arginine deiminase type-4). GSK484 potent
1093070-16-6 | GRL0617
(Catalog# : 2071625)
GRL0617 is a potent, selective and competitive noncovalent inhibitor of SARS PLPro. G
1191237-69-0 | GS-441524
(Catalog# : 2071546)
GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an
1622849-43-7 | GSK3145095
(Catalog# : 2071533)
GSK3145095 is a potent and orally active RIPK1 inhibitor (IC50 = 5 nM) with potential
1629063-81-5 | GNE-131
(Catalog# : 2071509)
GNE-131 is a Potent and Selective hNaV1.7 Inhibitor (Na V1.7 IC50 = 3 nM) for the Tre
1642581-63-2 | Glumetinib
(Catalog# : 203401)
Glumetinib, also known as SCC244, is a novel, potent and highly selective inhibitor o
1394121-05-1 | GNE-2861
(Catalog# : 111892)
GNE-2861 is a potent and exquisitely kinase-selective Group II PAK inhibitor (PAK4 Ki
1549811-53-1 | GSK-199
(Catalog# : 193293)
GSK199 is a selective PAD4 inhibitor with half-maximum inhibitory concentration (IC50
1637770-13-8 | GS-626510
(Catalog# : 193221)
GS-626510 is a potent BET family bromodomains inhibitor. It acts by targeting BRD2/3/
1445879-21-9 | GSK2837808A
(Catalog# : 193194)
GSK2837808A is a potent, selective lactate dehydrogenase A (LDHA) inhibitor (IC50 val
1536200-31-3 | GNE-9605
(Catalog# : 192284)
GNE-9605 is a highly potent, selective, and brain-penetrant aminopyrazole leucine-ric
1227911-45-6 | GSK2334470
(Catalog# : 192224)
GSK2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (
1032754-81-6 | GNE-477
(Catalog# : 192181)
GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor.
1373422-53-7 | GSKJ1
(Catalog# : 191255)
GSKJ1 is a selective and potent histone demethylase inhibitor (GSK-J1) that has signi
1150701-66-8 | GSK1940029
(Catalog# : 1812102)
GSK1940029, also known as SCD Inhibitor 1, is a SCD Inhibitor. GSK1940029 is a potent
1420367-28-7 | GSK2814338
(Catalog# : 181241)
GSK2814338, also known as Lp-PLA2 -IN-1, is a Lp-PLA2 inhibitor.
1642297-01-5 | GDC-0927
(Catalog# : 1811301)
GDC-0927, also known as SRN-927, is a next-generation oral SERD which appears to have
1923851-49-3 | GSK9311
(Catalog# : 1811233)
GSK9311 is a potent and highly selective inhibitor of the BRPF bromodomain (BRPDF1 pI
1404456-53-6 | GSK-2830371
(Catalog# : 1810292)
GSK 2830371 is a WiP1 inhibitor. It inhibits cell growth and tumor growth in lymphoma
1196541-47-5 | GDC-0575
(Catalog# : 189272)
GDC-0575 (ARRY-575, RG7741) is a potent and selective CHK1 inhibitor with an IC50 of
1025821-33-3 | GSK-626616
(Catalog# : 188241)
GSK 626616 is a YAK3/DYRK3 kinase inhibitor. It is a chemoprotective agent for the po
1373423-53-0 | GSK-J4 free base
(Catalog# : 187163)
GSK-J4 is a cell permeable, potent and selective histone demethylase.
1015787-98-0 | Gefapixant
(Catalog# : 187122)
Gefapixant, also known as AF-219 or MK-7264, is a P2X3 receptor antagonist. Gefapixan
1365970-03-1 | Glecaprevir
(Catalog# : 185311)
Glecaprevir, also known as ABT-493 and A-1282576, is a NS 3/4A inhibitor potentially
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2377000-84-3 | Dencatistat
(Catalog# : 25177)
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosph
1898207-64-1 | DS-1001b
(Catalog# : 25178)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.
1016340-64-9 | Z57346765
(Catalog# : 25191)
Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes
2416095-06-0 | CBR-470-1
(Catalog# : 25192)
CBR-470-1 is an Inhibitor of the glycolytic enzyme PGK1that induces Nrf2 activity.
1898206-17-1 | Safusidenib
(Catalog# : 25149)
Safusidenib, also known as DS-1001, is an oral isocitrate dehydrogenase [NADP] cytopl
2803470-63-3 | HC-7366
(Catalog# : 25076)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
146426-40-6 | Flavopiridol ( Alvocidib )
(Catalog# : 237071)
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is subst
2201056-66-6 | AG-270
(Catalog# : 25176)
MAT2A Inhibitor AG-270 is an orally available small molecule inhibitor of methionine
618913-30-7 | AZD-5904
(Catalog# : 181121)
AZD5904 is a potent orally bioavailable MPO inhibitor. In preclinical studies, AZD590
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa