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Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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Ubiquitin
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Cas Index 1
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Cas Index 1
1346546-69-7 | GSK872
(Catalog# : 17101621)
GSK872 is a a receptor interacting protein kinase-3 (RIP3) inhibitor. GSK872 inhibits
1539314-06-1 | GSK2881078
(Catalog# : 1791316)
GSK-2881078 is a selective androgen receptor modulator potentially for the treatment
1459687-96-7 | GJ-103 sodium
(Catalog# : 1791116)
GJ103 sodium salt is an active analog of the read-through compound GJ072.
1459687-89-8 | GJ-103 free acid
(Catalog# : 1791115)
GJ-103 is an active analog of the read-through compound GJ072. Chemical-induced read
199657-29-9 | Givinostat HCl
(Catalog# : 17919)
Givinostat or gavinostat, aslo known as ITF2357, is a potent and orally active histon
1350462-55-3 | Grazoprevir hydrate
(Catalog# : 1783018)
Grazoprevir, also known as MK5172, is a drug approved for the treatment of hepatitis
1496581-76-0 | GNE-3511
(Catalog# : 1781006)
GNE-3511 is a potent and selective dual leucine zipper kinase (DLK, MAP3K12) inhibito
1336960-13-4 | GSK2193874
(Catalog# : 178914)
GSK2193874 was identified as a selective, orally active TRPV4 blocker that inhibits C
1622848-92-3 | GSK2982772
(Catalog# : 178911)
GSK2982772 is an ATP competitive eceptor-interacting protein-1 (RIP1) kinase inhibit
1254036-77-5 | GSK2269557
(Catalog# : 2017883)
GSK2269557,also known as GSK-2269557, is a potent and selective PI3K inhibitor.
1282514-88-8 | GDC-0326
(Catalog# : 2017881)
GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kina
1007573-18-3 | GSK-1521498
(Catalog# : 20178215)
GSK-1521498 is a novel -Opioid receptor antagonist. It has been shown to attenuate re
1816331-63-1 | GSK321
(Catalog# : 2017821)
GSK321 is a potent and selective IDH1 mutant inhibitor. GSK321 potently inhibited int
1936428-93-1 | GNE-272
(Catalog# : 20178121)
GNE-272 is a potent and selective in Vivo Probe for the Bromodomains of CBP/EP300 (CB
156223-05-1 | GTS-21
(Catalog# : 16123016)
GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that
1910124-24-1 | GSK6853 (GSK-6853)
(Catalog# : 16123015)
GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhi
1346547-00-9 | GSK583
(Catalog# : 16123014)
GSK583 is a Highly Potent and Selective Inhibitor of RIP2 Kinase (RIP2K bing IC50=5 n
1010411-21-8 | GSK369796 Dihydrochloride
(Catalog# : 16123013)
GSK369796, also known as N-tert-butylisoquine, is an anti-malaria drug candidate. GSK
1619994-68-1 | GSK2801
(Catalog# : 16123012)
GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a
1224887-10-8 | GSK-2256098
(Catalog# : 16123011)
GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with
1014691-61-2 | GSK0660
(Catalog# : 16123009)
GSK0660 is a selective PPAR antagonist. GSK0660 differentially regulated 273 transcri
133053-19-7 | Go6983
(Catalog# : 16123008)
GO6983 is a potent protein kinase C (PKC) inhibitor. GO6893 displays cardioprotective
1362154-70-8 | GNE-617
(Catalog# : 16123007)
GNE-617 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with IC5
1628260-79-6 | GLPG-1690(ziritaxestat)
(Catalog# : 16123005)
GLPG1690 is a selective autotaxin inhibitor discovered by Galapagos, with potential a
1434048-34-6 | GDC-0853
(Catalog# : 16123004)
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potenti
1095173-27-5 | Glasdegib (PF-04449913)
(Catalog# : 16122787)
Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibit
136194-77-9 | Go6976
(Catalog# : 16122723)
Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat
1254036-66-2 | GSK2292767
(Catalog# : 16122702)
GSK2292767 is a potent and selective PI3K inhibitor.GSK2292767 is highly selective fo
1474110-21-8 | GSK2981278
(Catalog# : 6111521)
ROR modulator 1 is a retinoid-related orphan receptor gamma (RORy) modulator, extract
1616391-87-7 | GSK-591
(Catalog# : 6111009)
EPZ015866 (GSK591) is a potent selective inhibitor of the arginine methyltransferase
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
85622-93-1 | Temozolomide
(Catalog# : 25209)
Temozolomide is an alkylating agent.
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
2376397-93-0 | Opakalim
(Catalog# : 25193)
Opakalim (BHV-7000) is an oral, small-molecule activator of Kv7.2/7.3 potassium chann
2102501-84-6 | PF-06835919 ( MDK-1846 )
(Catalog# : 193264)
MDK1846 is a potent ketohexokinase (KHK) inhibitor.
2271348-04-8 | MK256
(Catalog# : 25208)
MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downreg
2351225-46-0 | NSD1 inhibitor BT5
(Catalog# : 25207)
BT5 potently inhibits NSD1, engages the SET domain in cells, and reduces H3K36me2 lev
1049704-18-8 | MA242 TFA
(Catalog# : 25206)
MA242 isMDM2 and NFAT1 dual inhibitorthat induces MDM2 auto-ubiquitination and degrad
2800223-30-5 | Dabogratinib ( TYRA-300 )
(Catalog# : 24073)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
N/A | AF710B
(Catalog# : 25205)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
2957874-18-7 | MAT2A inhibitor 5
(Catalog# : 25204)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit