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抑制剂/受体激动剂
Angiogenesis
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MAPK
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Stem Cells & Wnt
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
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Nuclear Receptor
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Amines
Amino Acids
Anilines
Boronic Acids
Bromides
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Deuterated
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
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Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
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On Sale
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公司简介
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产品名字索引 T
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产品名字索引 T
Tubercidin
(Catalog# : 16122718, Cas# :
69-33-0
)
Tubercidin, an adenosine analogue, is a nucleoside antibiotic. It is incorporated int
TPO agonist 1
(Catalog# : 6111515, Cas# :
1033040-23-1
)
TPO agonist 1 can increase production of platelets by stimulating the TPO receptor in
TY-52156
(Catalog# : 61118, Cas# :
934369-14-9
)
TY-52156 is a potent S1P3 receptor antagonist in a competitive manner, and the Ki val
TCS-OX2-29
(Catalog# : 61117, Cas# :
372523-75-6
)
TCS-OX2-29 is a potent and selective OX2 receptor antagonist with IC50 of 40 nM. Disp
THZ1
(Catalog# : 6111013, Cas# :
1604810-83-4
)
THZ1 is a novel selective and potent covalent CDK7 inhibitor with IC50(binding affini
TZ9
(Catalog# : 611934, Cas# :
1002789-86-7
)
TZ9 is a novel inhibitor of Rad6 ubiquitin conjugating enzyme(E2 enzyme); inhibits MD
THZ1-R
(Catalog# : 611926, Cas# :
1621523-07-6
)
THZ1-R is a non-cysteine reactive analog, which displays diminished activity for CDK7
THZ1 Hydrochloride
(Catalog# : 611925)
THZ1 Hcl is a novel selective and potent covalent CDK7 inhibitor with IC50(binding af
TGR-1202 hydrochloride
(Catalog# : 611905, Cas# :
1532533-78-0
)
TGR-1202 hydrochloride is an orally available, next generation PI3Kdelta inhibitor, i
TDZD-8
(Catalog# : 161009029, Cas# :
327036-89-5
)
TDZD-8 protects the brain against I/R injury by inhibiting GSK-3beta activity. TDZD-8
Tideglusib
(Catalog# : 9028, Cas# :
865854-05-3
)
Tideglusib protects neural stem cells against NMDA receptor overactivation. Tideglusi
TWS-119
(Catalog# : 161009027, Cas# :
601514-19-6 (free base); 1507095-58-0 (2 TFA salt)
)
TWS119 could activate Wnt/-catenin pathway and up-regulate the expression of CD62L in
Triciribine
(Catalog# : 161009022, Cas# :
35943-35-2
)
Triciribine inhibits the phosphorylation, activation, and signalling of Akt-1, -2, an
Tacrolimus
(Catalog# : 161009006, Cas# :
104987-11-3
)
It is also used in a topical preparation in the treatment of atopic dermatitis (eczem
TG100713
(Catalog# : 160926017, Cas# :
925705-73-3
)
TG100713 is an inhibitor of PI3-kinase (IC50 values are 24, 50, 165 and 215 nM for PI
TG100-115
(Catalog# : 160926011, Cas# :
677297-51-7
)
TG100-115, inhibited PI3K and -(IC50 values of 83 and 235 nM, respectively), whereas
Taltirelin
(Catalog# : 16071029, Cas# :
103300-74-9
)
Taltirelin
TMP-195
(Catalog# : 16071020, Cas# :
1314891-22-9
)
TMP-195
TC-G 1008
(Catalog# : 16071003, Cas# :
1621175-65-2
)
TC-G 1008,
T-5224
(Catalog# : 16070909, Cas# :
530141-72-1
)
T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates live
Tanespimycin
(Catalog# : 16070805, Cas# :
75747-14-7
)
Tanespimycin, also known as 17-AAG, is an orally bioavailable, small-molecule inhibit
Taladegib
(Catalog# : 121414, Cas# :
1258861-20-9
)
Taladegib is a potent Hedgehog inhibitor with potential anticancer activity, which in
Tivantinib
(Catalog# : 16070802, Cas# :
905854-02-6
)
Tivantinib (ARQ-197) is an orally bioavailable small molecule inhibitor of c-Met with
TAK-580 (MLN2480)
(Catalog# : 16062203, Cas# :
1096708-71-2
)
TAK-580, also known as MLN2480, BIIB024, and AMG 2112819, is an oral, selective pan-R
trovirdine
(Catalog# : 16060302, Cas# :
149488-17-5
)
trovirdine
Taprenepag(CP-544326)
(Catalog# : 652601, Cas# :
752187-80-7
)
Taprenepag is the active metabolite of PF-04217329.
Trofinetide
(Catalog# : 032406, Cas# :
853400-76-7
)
Trofinetide is a glypromate (or Gly-Pro-Glu) analog and neuroprotectant.
Tyrosine kinase inhibitor
(Catalog# : 030302, Cas# :
1021950-26-4
)
Coming soon!
Tenalisib
(Catalog# : 012009, Cas# :
1639417-53-0 or 1693773-94-2
)
Tenalisib is a potent and selective dual PI3K/ inhibitor that inhibited growth of B-c
Tanzisertib
(Catalog# : 011903, Cas# :
899805-25-5
)
Tanzisertib is a potent, selective, and orally active JNK inhibitor with potential an
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
----
SSTR
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
----
Hemoglobin
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Linafexor (别名: CS-0159)
(Catalog# : 26A089, Cas# :
2765593-43-7
)
Linafexor(同义词:CS-0159)是法尼醇X受体(FXR)的强效非胆汁酸激
Prifetrastat (Synonyms: PF-07248144)
(Catalog# : 26A088, Cas# :
2569008-99-5
)
Prifetrastat (Synonyms: PF-07248144) 是一款首创、选择性、口服活性的
Camonsertib
(Catalog# : 24052, Cas# :
2417489-10-0
)
Camonsertib,也称为RP 3500,是一种新型、强效和选择性的ATR抑制剂,
MRX-2843
(Catalog# : 26A087, Cas# :
1429882-07-4
)
MRX-2843 是一种口服可用的双受体酪氨酸激酶(RTKs)抑制剂,作用
GDC-0134
(Catalog# : 20432, Cas# :
1637394-01-4
)
GDC-0134是一种MAP3K12(DLK)抑制剂。
BI-847325
(Catalog# : 25046, Cas# :
2128698-24-6
)
BI-847325是一种新型的、可口服的、竞争ATP结合位点的Aurora激酶和M
GDD-261
(Catalog# : 26A084, Cas# :
3137699-54-5
)
GDD-261是一种口服活性的磷酸甘油酸脱氢酶变构抑制剂(IC50=61nM)
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib(IMM-1-104)是一种口服的小分子MEK1和MEK2激酶变构抑制剂
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643是一种新型、口服、非共价、大环、突变选择性OMNI-EGFR抑制
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。