T-0901317
编号: 16122840
Cas号: 293754-55-9
纯度: 98%
T-0901317, also known as T-1317; TO-091317; TO 901317, is a liver X receptor (LXR) agonist. T-0901317 inhibits development of atherosclerosis in LDL receptor-deficient mice. T-0901317 significantly reduced the atherosclerotic lesions in LDLR(-/-) mice without affecting plasma total cholesterol levels. T-0901317 increased expression of ATP binding cassette A1 in the lesions in LDLR(-/-) mice as well as in mouse peritoneal macrophages. T-0901317 also significantly induced cholesterol efflux activity in peritoneal macrophages. T-0901317 may be useful therapeutic agents for the treatment of atherosclerosis.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | T-0901317 |
|---|---|
| Iupac 化学名称 | T-0901317 |
| 同义词 | TO-091317; TO 091317; TO091317; T-0901317; T-1317; TO-91317; TO 901317; T0901317; T1317; TO91317; TO901317 |
| 英文同义词 | TO-091317; TO 091317; TO091317; T-0901317; T-1317; TO-91317; TO 901317; T0901317; T1317; TO91317; TO901317 |
| 分子式 | C17H12F9NO3S |
| 分子量 | 481.3326 |
| Smile | c1ccc(cc1)S(=O)(=O)N(CC(F)(F)F)c2ccc(cc2)C(C(F)(F)F)(C(F)(F)F)O |
| InChiKey | SGIWFELWJPNFDH-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 |
| Cas号 | 293754-55-9 |
| MDL | MFCD03412028 |
| 相关CAS号 |
订购信息
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| 大货 | 询价 | 询价 | 询价 |
