Tivantinib
编号: 16070802
Cas号: 905854-02-6
纯度: 98% by HPLC
Tivantinib (ARQ-197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity. c-Met inhibitor ARQ 197 binds to the c-Met protein and disrupts c-Met signal transduction pathways, which may induce cell death in tumor cells overexpressing c-Met protein or expressing consitutively activated c-Met protein. c-Met protein, the product of the proto-oncogene c-Met, is a receptor tyrosine kinase also known as hepatocyte growth factor receptor (HGFR); this protein is overexpressed or mutated in many tumor cell types and plays key roles in tumor cell proliferation, survival, invasion, and metastasis, and tumor angiogenesis. Check for active clinical trials or closed clinical trials using this agent.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Tivantinib |
|---|---|
| Iupac 化学名称 | (3R,4R)-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione |
| 同义词 | ARQ197 Tivantinib |
| 英文同义词 | ARQ197 Tivantinib |
| 分子式 | C23H19N3O2 |
| 分子量 | 369.41 |
| Smile | C1(=CN2CCCC3=CC=CC1=C23)[C@@H]2C(NC([C@H]2C2=CNC3=CC=CC=C23)=O)=O |
| InChiKey | UCEQXRCJXIVODC-PMACEKPBSA-N |
| InChi | InChI=1S/C23H19N3O2/c27-22-19(16-11-24-18-9-2-1-7-14(16)18)20(23(28)25-22)17-12-26-10-4-6-13-5-3-8-15(17)21(13)26/h1-3,5,7-9,11-12,19-20,24H,4,6,10H2,(H,25,27,28)/t19-,20-/m0/s1 |
| Cas号 | 905854-02-6 |
| 相关CAS号 |
订购信息
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| 大货 | 询价 | 询价 | 询价 |
