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Catalog No.: 61118
Cas No.: 934369-14-9
Purity : 98% 
61118 - TY-52156 | CAS 934369-14-9

Catalog number : 61118

CAS number : 934369-14-9

分子式 : C18H19Cl2N3O 

分子量 : 364.27 

Iupac 化学名称 : TY-52156 

InChiKey :

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同义词TY52156; TY 52156 
英文同义词TY52156; TY 52156 
外观crystalline solid 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
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TY-52156 is a potent S1P3 receptor antagonist in a competitive manner, and the Ki value is estimated to be 110 nM for S1P3 receptor.

TY-52156 shows submicromolar potency and a high degree of selectivity for S1P3 receptor. TY-52156 is both sensitive and useful as an S1P3 receptor-specific antagonist and reveal that S1P induces vasoconstriction by directly activating S1P3 receptor and through a subsequent increase in [Ca2+]i and Rho activation in vascular smooth muscle cells. TY-52156 has a selective antagonistic effect toward S1P3 receptor.

TY-52156 Suppresses S1P3 Receptor-Induced Bradycardia In Vivo.  the oral administration of TY-52156 inhibits S1P3 receptor-dependent bradycardia.


934369-14-9 - Request Bulk Quote

934369-14-9 - Request Bulk Quote