+86-27-65522453 sales@sun-shinechem.com

TY-52156

Catalog No.: 61118
Cas No.: 934369-14-9
Purity : 98% 
61118 - TY-52156 | CAS 934369-14-9

Catalog number : 61118

CAS number : 934369-14-9

分子式 : C18H19Cl2N3O 

分子量 : 364.27 

Iupac 化学名称 : TY-52156 

InChiKey :

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDS电话:+86-27-65522453 | Email:sales@sun-shinechem.com
同义词TY52156; TY 52156 
英文同义词TY52156; TY 52156 
分子式C18H19Cl2N3O 
分子量364.27 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
InChiKey
InChi
Coming soon.

TY-52156 is a potent S1P3 receptor antagonist in a competitive manner, and the Ki value is estimated to be 110 nM for S1P3 receptor.

TY-52156 shows submicromolar potency and a high degree of selectivity for S1P3 receptor. TY-52156 is both sensitive and useful as an S1P3 receptor-specific antagonist and reveal that S1P induces vasoconstriction by directly activating S1P3 receptor and through a subsequent increase in [Ca2+]i and Rho activation in vascular smooth muscle cells. TY-52156 has a selective antagonistic effect toward S1P3 receptor.

TY-52156 Suppresses S1P3 Receptor-Induced Bradycardia In Vivo.  the oral administration of TY-52156 inhibits S1P3 receptor-dependent bradycardia.


 

934369-14-9 - Request Bulk Quote

×
934369-14-9 - Request Bulk Quote
Change