TWS-119
编号: 161009027
Cas号: 601514-19-6 (free base); 1507095-58-0 (2 TFA salt)
纯度: 98% by HPLC
TWS119 could activate Wnt/-catenin pathway and up-regulate the expression of CD62L in a dose-dependent manner, but it decreased the expression of CD107a. Glycogen synthase kinase (GSK)-3, a constitutively active serine-threonine kinase, acts as a key regulator of major signaling pathways, including the Wnt, Hedgehog, and Notch pathways.
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化学信息
| 名称 | TWS-119 |
|---|---|
| Iupac 化学名称 | 3-((6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)phenol |
| 同义词 | TWS-119; TWS119; TWS 119. |
| 英文同义词 | TWS-119; TWS119; TWS 119. |
| 分子式 | C18H14N4O2 |
| 分子量 | 318.34 |
| Smile | NC=1C=C(C=CC1)C1=CC2=C(N=CN=C2OC=2C=C(C=CC2)O)N1 |
| InChiKey | VPVLEBIVXZSOMQ-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22) |
| Cas号 | 601514-19-6 (free base); 1507095-58-0 (2 TFA salt) |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
