Taladegib
Catalog No.: 121414
Cas No.: 1258861-20-9
Purity : 98%
Catalog number : 121414
CAS number : 1258861-20-9
分子式 : C26H24F4N6O
分子量 : 512.502
Iupac 化学名称 : 4-fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide
Smile : O=C(N(C)C1CCN(C2=NN=C(C3=CC=NN3C)C4=C2C=CC=C4)CC1)C5=CC=C(F)C=C5C(F)(F)F
InChiKey : SZBGQDXLNMELTB-UHFFFAOYSA-N
| Packaging | Price | Availability | Purity | Estimated Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry |
| 同义词 | LY2940680; LY2940680; LY2940680 |
|---|---|
| 英文同义词 | LY2940680; LY2940680; LY2940680 |
| 分子式 | C26H24F4N6O |
| 分子量 | 512.502 |
| 外观 | Solid powder |
| 纯度 | 98% |
| 可溶性 | Soluble in DMSO |
| 存储 | -20 ºC for 3 years |
| 运输条件 | Shipped under ambient temperature |
| Smile | O=C(N(C)C1CCN(C2=NN=C(C3=CC=NN3C)C4=C2C=CC=C4)CC1)C5=CC=C(F)C=C5C(F)(F)F |
| InChiKey | SZBGQDXLNMELTB-UHFFFAOYSA-N |
| InChi | InChI=1S/C26H24F4N6O/c1-34(25(37)20-8-7-16(27)15-21(20)26(28,29)30)17-10-13-36(14-11-17)24-19-6-4-3-5-18(19)23(32-33-24)22-9-12-31-35(22)2/h3-9,12,15,17H,10-11,13-14H2,1-2H3 |
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Taladegib is a potent Hedgehog inhibitor with potential anticancer activity, which inhibits cancer growth in cell lines containing a mutation in the gene encoding Smoothened that researchers had previously observed in patient with cancer who developed resistance to vismodegib.
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