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Triciribine

编号: 161009022
Cas号: 35943-35-2
纯度: 98% by HPLC 

Triciribine inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation. Akts are anti-apoptotic serine/theronine-specific protein kinases that phosphorylate and inactivate components of the apoptotic machinery, including Bcl-xL/Bcl-2-associated death promoter (BAD) and caspase 9. Check for active clinical trials or closed clinical trials using this agent. 

仅供研究使用。 我们不向患者出售。

化学信息

名称Triciribine
Iupac 化学名称(2R,3R,4S,5R)-2-(3-amino-5-methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. 
同义词VQD002TCNPtriciribineTricyclic nucleoside; PentaazacentopthyleneAPI2Akt Inhibitor V. 
英文同义词VQD002TCNPtriciribineTricyclic nucleoside; PentaazacentopthyleneAPI2Akt Inhibitor V. 
分子式C13H16N6O4 
分子量320.3 
SmileCN1c2c3c(cn(c3ncn2)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)C(=N1)N
InChiKeyHOGVTUZUJGHKPL-HTVVRFAVSA-N
InChiInChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1
Cas号35943-35-2
MDLMFCD00932413
相关CAS号

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外观性状Solid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

161009022 - Triciribine | CAS 35943-35-2

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