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Tubercidin

Catalog No.: 16122718
Cas No.: 69-33-0
Purity : 98% 
16122718 - Tubercidin | CAS 69-33-0

Catalog number : 16122718

CAS number : 69-33-0

分子式 : C11H14N4O4 

分子量 : 266.25 

Iupac 化学名称 : Tubercidin 

Smile : c1cn(c2c1c(ncn2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O

InChiKey : HDZZVAMISRMYHH-KCGFPETGSA-N

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同义词7-deaza-adenosine 
英文同义词7-deaza-adenosine 
分子式C11H14N4O4 
分子量266.25 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
Smilec1cn(c2c1c(ncn2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
InChiKeyHDZZVAMISRMYHH-KCGFPETGSA-N
InChiInChI=1S/C11H14N4O4/c12-9-5-1-2-15(10(5)14-4-13-9)11-8(18)7(17)6(3-16)19-11/h1-2,4,6-8,11,16-18H,3H2,(H2,12,13,14)/t6-,7-,8-,11-/m1/s1
MDLMFCD00056012
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Tubercidin, an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.Tubercidin at the dose regimen (5 mg/kg everyday for 4 days) is lethal when used alone. Some of the studies show that the mortality from tubercidin is primarily due to hepatic and renal injuries and, to a lesser extent, damage to the pancreas. Coadministration of NBMPR-P at 25 mg/kg per day completely protects the mice (100% survival) from this lethal dose regimen of tubercidin 

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