武汉永璨生物科技有限公司
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抑制剂/受体激动剂
Angiogenesis
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MAPK
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Metabolism
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Protein Tyrosine Kinase
Proteases
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Stem Cells & Wnt
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Ubiquitin
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分子砌块
Aldehydes
Amines
Amino Acids
Anilines
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Bromides
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Deuterated
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 G
GSK2981278
(Catalog# : 6111521, Cas# :
1474110-21-8
)
ROR modulator 1 is a retinoid-related orphan receptor gamma (RORy) modulator, extract
GSK163090
(Catalog# : 6111015, Cas# :
844903-58-8
)
GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist wi
GSK-591
(Catalog# : 6111009, Cas# :
1616391-87-7
)
EPZ015866 (GSK591) is a potent selective inhibitor of the arginine methyltransferase
GSK2269557 free base
(Catalog# : 611826, Cas# :
1254036-71-9
)
GSK-2269557 (free base) is a potent and selective PI3Kδ inhibitor over the closely r
GSK2141795 (hydrochloride)
(Catalog# : 611807, Cas# :
1047635-80-2
)
GSK2141795 Hcl is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM
GSK-690693
(Catalog# : 161009019, Cas# :
937174-76-0
)
Pan-AKT kinase inhibitor GSK-690693 binds to and inhibits Akt kinases 1, 2, and 3, wh
GX-674
(Catalog# : 1681201, Cas# :
1432913-36-4
)
GX-674 is an aryl sulfonamide class of antagonists that inhibits Nav1.7.Nav (voltage-
GDC-0084
(Catalog# : 16071405, Cas# :
1382979-44-3
)
GDC-0084, also known as RG7666, is a phosphatidylinositol 3-kinase (PI3K) inhibitor w
Gilteritinib
(Catalog# : 16071108, Cas# :
1254053-43-4
)
Gilteritinib, also known as (ASP2215, is a potent FLT3/AXL inhibitor, which showed po
GDC-0152
(Catalog# : 16071101, Cas# :
873652-48-3
)
GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of
GSK-461364
(Catalog# : 16071032, Cas# :
929095-18-1
)
GSK-461364 is a Polo-like kinase 1 inhibitor, is also a small molecule Polo-like kina
GPI-1046
(Catalog# : 16071027, Cas# :
186452-09-5
)
GPI-1046
GBR 12783
(Catalog# : 16071019, Cas# :
67469-57-2
)
GBR 12783
GW4064
(Catalog# : 16071018, Cas# :
278779-30-9
)
GW-4064 is a selective agonist of FXR (EC50 = 15 nM).2 It displays no activity at oth
GSK621
(Catalog# : 16070905, Cas# :
1346607-05-3
)
GSK621 is a specific and potentAMPKactivator.
GSK1210151A
(Catalog# : 16070808, Cas# :
1300031-49-5
)
GSK1210151A, also known as I-BET151, is a BET bromodomain inhibitor, which blocks rec
GDC-0994
(Catalog# : 16062801, Cas# :
1453848-26-4
)
GDC-0994, also known as RG7842, is an orally available inhibitor of extracellular sig
GNF-7
(Catalog# : 16060604, Cas# :
839706-07-9
)
BenzaMide
GR148672X
(Catalog# : 032404, Cas# :
263890-70-6
)
Coming soon!
GW501516
(Catalog# : 030905, Cas# :
317318-70-0
)
Coming soon!
Glesatinib(MGCD-265)
(Catalog# : 012001, Cas# :
936694-12-1
)
Glesatinib is a potent tyrosine kinase inhibitor with potential antineoplastic activi
Gamma-Secretase Modulators
(Catalog# : 011909, Cas# :
937812-80-1
)
Coming soon!
GLYX 13
(Catalog# : 011809, Cas# :
117928-94-6
)
Coming soon!
GDC-0623
(Catalog# : 010811, Cas# :
1168091-68-6
)
GDC-0623 is a potent, ATP-uncompetitive inhibitors of MEK1(Ki=0.13 nM, +ATP); 6-fold
Gepotidacin
(Catalog# : 010610, Cas# :
1075236-89-3
)
Gepotidacin is a potent Type II DNA topoisomerase inhibitor. Gepotidacin is a novel a
GGTI-298
(Catalog# : 010609, Cas# :
1217457-86-7
)
GGTI-298 is a potent geranylgeranyltransferase-I (GGTase-I) inhibitor with potential
Givinostat
(Catalog# : 123008, Cas# :
497833-27-9
)
Givinostat is an orally bioavailable hydroxymate inhibitor of histone deacetylase (HD
GSK2838232
(Catalog# : 122924, Cas# :
1443461-21-9
)
GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed f
GW2580
(Catalog# : 122524, Cas# :
870483-87-7
)
GW2580 is an orally bioavailable inhibitor of c-FMS kinase; completely inhibited huma
GSK-LSD1 2HCl
(Catalog# : 122505, Cas# :
1431368-48-7
)
Coming soon!
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive-Oxygen-Species-ROS
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Mitoquinol mesylate (MitoQ)
(Catalog# : 26A042, Cas# :
845959-55-9
)
Mitoquinol mesylate (MitoQ) 是一种线粒体靶向抗氧化剂,具体而言,它
SPG-601 ( VSN-16R )
(Catalog# : 24042, Cas# :
1246960-09-7
)
SPG-601(原名VSN-16R)是一种口服给药、同类首创的小分子药物,是
LY3039478 ( Crenigacestat )
(Catalog# : 17021601, Cas# :
1421438-81-4
)
LY3039478 ( Crenigacestat ) 是一种选择性 NOTCH1 抑制剂,通过阻断 VEGFA/
PF-9366
(Catalog# : 184107, Cas# :
72882-78-1
)
PF-9366是一种新型的人蛋氨酸腺苷转移酶2A (Mat2A),肝外同种型。
MAT2A-IN-22
(Catalog# : 26A021, Cas# :
2925330-18-1
)
MAT2A-IN-22 (Compound 29-1) 是一种可透过血脑屏障的和口服有效的 MAT2A
Pantothenate kinase-IN-3
(Catalog# : 26A041)
泛酸激酶-IN-3(亦称化合物21,https://doi.org/10.1021/acs.jmedchem.5c03452)
Claziprotamidum ( Claziprotamide ; BBP-671 )
(Catalog# : 26A040, Cas# :
2361124-03-8
)
Claziprotamidum(Claziprotamide;BBP-671)是一种强效、口服有效且能透过
PZ-3022
(Catalog# : 26A039, Cas# :
2170608-85-0
)
PZ-3022是一种别构型的PanK激活剂,能够抵消C3-CoA的抑制作用。
PZ-2891
(Catalog# : 193282, Cas# :
2170608-82-7
)
PZ-2891是一种强效的、选择性的、口服活性泛酸激酶(PANK)调制剂,
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,