GDC-0084
编号: 16071405
Cas号: 1382979-44-3
纯度: 98% by HPLC
GDC-0084, also known as RG7666, is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor GDC-0084 specifically inhibits PI3K in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in the inhibition of both cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis.
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化学信息
| 名称 | GDC-0084 |
|---|---|
| Iupac 化学名称 | 5-(6,6-dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[4,3-e]purin-2-yl)pyrimidin-2-amine |
| 同义词 | RG7666; RG-7666 |
| 英文同义词 | RG7666; RG-7666 |
| 分子式 | C18H22N8O2 |
| 分子量 | 382.428 |
| Smile | CC1(OCCN2C=3N=C(N=C(C3N=C21)N2CCOCC2)C=2C=NC(=NC2)N)C |
| InChiKey | LGWACEZVCMBSKW-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H22N8O2/c1-18(2)16-22-12-14(25-3-6-27-7-4-25)23-13(11-9-20-17(19)21-10-11)24-15(12)26(16)5-8-28-18/h9-10H,3-8H2,1-2H3,(H2,19,20,21) |
| Cas号 | 1382979-44-3 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
