GSK1210151A
编号: 16070808
Cas号: 1300031-49-5
纯度: 98% by HPLC
GSK1210151A, also known as I-BET151, is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. I-BET151 ( GSK1210151A ) shows good oral bioavailability in both the rat and minipig as well as demonstrating efficient suppression of bacterial induced inflammation and sepsis in a murine in vivo endotoxaemia model.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | GSK1210151A |
|---|---|
| Iupac 化学名称 | 7-(3,5-dimethylisoxazol-4-yl)-8-methoxy-1-((R)-1-(pyridin-2-yl)ethyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one |
| 同义词 | IBET151; IBET-151; |
| 英文同义词 | IBET151; IBET-151; |
| 分子式 | C23H21N5O3 |
| 分子量 | 415.44 |
| Smile | CC1=NOC(=C1C=1C(=CC=2C3=C(C=NC2C1)NC(N3[C@H](C)C3=NC=CC=C3)=O)OC)C |
| InChiKey | VUVUVNZRUGEAHB-CYBMUJFWSA-N |
| InChi | InChI=1S/C23H21N5O3/c1-12-21(14(3)31-27-12)16-9-18-15(10-20(16)30-4)22-19(11-25-18)26-23(29)28(22)13(2)17-7-5-6-8-24-17/h5-11,13H,1-4H3,(H,26,29)/t13-/m1/s1 |
| Cas号 | 1300031-49-5 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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