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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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others
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Anilines
Boronic Acids
Bromides
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Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyrimidines
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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Custom Synthesis
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Name Index M
MK-571 sodium salt
(Catalog# : 16123055, Cas# :
115104-28-4
)
MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the bindin
Mizoribine
(Catalog# : 16123053, Cas# :
50924-49-7
)
Mizoribine,Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug. The co
Mivebresib
(Catalog# : 16123052, Cas# :
1445993-26-9
)
Mivebresib, also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-cont
Mitoxantrone HCl
(Catalog# : 16123051, Cas# :
65271-80-9
)
Mitoxantrone hydrochloride is the hydrochloride salt of an anthracenedione antibiotic
Mirin
(Catalog# : 16123049, Cas# :
1198097-97-0
)
Mirin is a Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor.
Migalastat HCl
(Catalog# : 16123048, Cas# :
75172-81-5
)
Migalastat HCl, also known as AT1001 or GR181413A, is a pharmacological chaperone tha
MI-2 (MALT1 inhibitor)
(Catalog# : 16123047, Cas# :
1047953-91-2
)
MI-2 is a MALT1 inhibitor (IC50 = 5.84 M). MI-2 binds directly to MALT1 and irreversi
MG-101
(Catalog# : 16123046, Cas# :
110044-82-1
)
MG-101, also known as Calpain Inhibitor I and ALLN, is a calpain inhibitor (IC50 = 0.
Mertansine (DM1)
(Catalog# : 16123045, Cas# :
139504-50-0
)
Mertansine refers to the thiol-containing maytansinoid, DM1 (N2-deacetyl-N2-(3-mercap
Medroxyprogesterone Acetate
(Catalog# : 16123044, Cas# :
71-58-9
)
Medroxyprogesterone Acetate, also known as MPA, is a steroidal progestin, a synthetic
MC-976
(Catalog# : 16122832, Cas# :
129831-99-8
)
MC-976 is an Vitamin D3 derivative.
Mafodotin
(Catalog# : 16122831, Cas# :
863971-19-1
)
Mafodotin, also known as mc-MMAF and SGD-1269 or Maleimidocaproyl monomethylauristati
Madrasin
(Catalog# : 16122830, Cas# :
374913-63-0
)
Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the e
M2I-1
(Catalog# : 16122829, Cas# :
312271-03-7
)
M2I-1, also known as Mad2 Inhibitor-1, is Protein-Protein Interaction Inhibitor Targe
MK571
(Catalog# : 161227105, Cas# :
115103-85-0
)
MK-571 is a selective, orally active CysLT1 receptor(Cysteinyl leukotriene receptor)
MPTP hydrochloride
(Catalog# : 16122796, Cas# :
23007-85-4
)
MPTP hydrochloride is a dopaminergic neurotoxin and cause selective destruction of do
ML323
(Catalog# : 16122790, Cas# :
1572414-83-5
)
ML323 is a highly potent and selective USP1-UAF1 inhibitor with IC50 of 76 nM.ML323 i
ML390
(Catalog# : 16122749)
ML390 is a human DHODH inhibitor that induces differentiation in acute myeloid leukem
MRT67307
(Catalog# : 16122745, Cas# :
1190378-57-4
)
MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, re
MK-4827(Niraparib) tosylate
(Catalog# : 16122717, Cas# :
1038915-73-9
)
MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8
MP-A08
(Catalog# : 6111524, Cas# :
219832-49-2
)
MP-A08 is a highly selective ATP competitive SK inhibitor that targets both SK1 and S
Mcl1-IN-2
(Catalog# : 6111404, Cas# :
292057-76-2
)
Mcl1-IN-2 is a Mcl-1 inhibitor without reported IC50 value.
Marinopyrrole A
(Catalog# : 6111403, Cas# :
1227962-62-0
)
Marinopyrrole (Maritoclax) is a novel and specific Mcl-1 inhibitor with an IC50 value
ML224
(Catalog# : 61116, Cas# :
1338824-21-7
)
ML224(NCGC00242364; ANTAG3) is a selective TSHR inverse agonist; inhibits TSH-stimula
(±)-Methotrimeprazine D6
(Catalog# : 61114, Cas# :
1189805-51-3
)
()-Methotrimeprazine (D6) is the deuterium labeled Methotrimeprazine, which is a D3 d
Motolimod
(Catalog# : 6111017, Cas# :
926927-61-9
)
Motolimod
MCC950 sodium
(Catalog# : 6111014, Cas# :
256373-96-3
)
MCC950 (CP 456773) sodium is a potent, selective, small molecule inhibitor of NLRP3 w
MS023
(Catalog# : 6111012, Cas# :
1831110-54-3
)
MS023 is a potent, selective, and cell-active inhibitor of human type I PRMTs with IC
MK-4101
(Catalog# : 6111008, Cas# :
935273-79-3
)
MK-4101 is a potent SMO Inhibitor of the Hedgehog PathwayMK-4101 is a potent SMO Inhi
ML346
(Catalog# : 611940, Cas# :
100872-83-1
)
ML346 is a novel activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).