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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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Name Index M
Merimepodib
(Catalog# : 17030308, Cas# :
198821-22-6
)
Merimepodib, also known as VX-497, is orally bioavailable IMPDH inhibitor, which inhi
ML-264
(Catalog# : 17030302, Cas# :
1550008-55-3
)
ML-264 is a Krppel-like factor 5 (KLF5) inhibitor That Potently Inhibits Growth of Co
MK-8245
(Catalog# : 17030109, Cas# :
1030612-90-8
)
MK-8245 is a potent, liver-targeted SCD inhibitor with preclinical antidiabetic and a
MLN-1117
(Catalog# : 17030101, Cas# :
1268454-23-4
)
Serabelisib (also known as MLN1117, INK1117, and TAK-117) is an orally bioavailable i
ML-281
(Catalog# : 17022811, Cas# :
1404437-62-2
)
ML-281 is a potent ans selective STK33 inhibitor (IC50 = 14 nM). ML281 showed low nan
Maraviroc
(Catalog# : 17022804, Cas# :
376348-65-1
)
Maraviroc (UK-427857; Selzentry; Celsentri) is a selective CCR5 antagonist (IC50= 6.4
MMAE (Monomethyl auristatin E)
(Catalog# : 17022403, Cas# :
474645-27-7
)
MMAE, also known as Monomethyl auristatin E, is a synthetic antineoplastic agent. Bec
Monastrol
(Catalog# : 17021322, Cas# :
329689-23-8
)
Monastrol is a cell-permeable small molecule inhibitor of kinesin-5(KIF11) which is
MS049
(Catalog# : 17021313, Cas# :
1502816-23-0
)
MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM
Miransertib(ARQ 092)
(Catalog# : 17021301, Cas# :
1313883-00-9
)
ARQ 092 is a novel, orally bioavailable and selective AKT pathway inhibitor exhibit
MT-DADMe-ImmA(MTDIA HCl)
(Catalog# : 712101, Cas# :
1399840-35-7
)
Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-pm inhibitor of human 5-methyl
7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
(Catalog# : 17011908, Cas# :
7752-54-7
)
7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
ML-7
(Catalog# : 17011107, Cas# :
110448-33-4
)
ML-7 is an inhibitor of smooth muscle myosin light chain kinase (MLCK) with a Ki
MX69
(Catalog# : 17011105, Cas# :
1005264-47-0
)
MX69 is a MDM2/XIAP inhibitor, used for cancer treatment.
MK-571 sodium salt
(Catalog# : 16123055, Cas# :
115104-28-4
)
MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the bindin
Mizoribine
(Catalog# : 16123053, Cas# :
50924-49-7
)
Mizoribine,Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug. The co
Mivebresib
(Catalog# : 16123052, Cas# :
1445993-26-9
)
Mivebresib, also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-cont
Mitoxantrone HCl
(Catalog# : 16123051, Cas# :
65271-80-9
)
Mitoxantrone hydrochloride is the hydrochloride salt of an anthracenedione antibiotic
Mirin
(Catalog# : 16123049, Cas# :
1198097-97-0
)
Mirin is a Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor.
Migalastat HCl
(Catalog# : 16123048, Cas# :
75172-81-5
)
Migalastat HCl, also known as AT1001 or GR181413A, is a pharmacological chaperone tha
MI-2 (MALT1 inhibitor)
(Catalog# : 16123047, Cas# :
1047953-91-2
)
MI-2 is a MALT1 inhibitor (IC50 = 5.84 M). MI-2 binds directly to MALT1 and irreversi
MG-101
(Catalog# : 16123046, Cas# :
110044-82-1
)
MG-101, also known as Calpain Inhibitor I and ALLN, is a calpain inhibitor (IC50 = 0.
Mertansine (DM1)
(Catalog# : 16123045, Cas# :
139504-50-0
)
Mertansine refers to the thiol-containing maytansinoid, DM1 (N2-deacetyl-N2-(3-mercap
MC-976
(Catalog# : 16122832, Cas# :
129831-99-8
)
MC-976 is an Vitamin D3 derivative.
Mafodotin
(Catalog# : 16122831, Cas# :
863971-19-1
)
Mafodotin, also known as mc-MMAF and SGD-1269 or Maleimidocaproyl monomethylauristati
Madrasin
(Catalog# : 16122830, Cas# :
374913-63-0
)
Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the e
M2I-1
(Catalog# : 16122829, Cas# :
312271-03-7
)
M2I-1, also known as Mad2 Inhibitor-1, is Protein-Protein Interaction Inhibitor Targe
MK571
(Catalog# : 161227105, Cas# :
115103-85-0
)
MK-571 is a selective, orally active CysLT1 receptor(Cysteinyl leukotriene receptor)
MPTP hydrochloride
(Catalog# : 16122796, Cas# :
23007-85-4
)
MPTP hydrochloride is a dopaminergic neurotoxin and cause selective destruction of do
ML323
(Catalog# : 16122790, Cas# :
1572414-83-5
)
ML323 is a highly potent and selective USP1-UAF1 inhibitor with IC50 of 76 nM.ML323 i
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran