Search By Initial

Name Index M

• MDK35833 (Catalog# : 179114, Cas# : 1016535-83-3)MDK35833, also known as Oct3/4-inducer-1, is a potent Oct3/4-inducer. MDK35833 can promot expression and stabilization of Oct3/4 and enhance its transcriptional activity in diver
• ML241 HCl (Catalog# : 179111, Cas# : 2070015-13-1)ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase with IC(50) values of 100 nM.
• ML364 (Catalog# : 179833, Cas# : 1991986-30-1)ML364 is a small molecule inhibitor of the deubiquitinase USP2 with potential anticancer activity.
• Mitoxantrone HCl (Catalog# : 179827, Cas# : 70476-82-3)Mitoxantrone hydrochloride is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA.
• ML311 (Catalog# : 179826, Cas# : 315698-17-0)ML311, also known as EU-5346, is a potent and selective inhibitor of the Protein-Protein Interaction of Mcl-1 and Bim. ML311 Potently and Selectively Disrupts the Protein-Protein
• ML-18 (Catalog# : 179810, Cas# : 1422269-30-4)ML18 is Bombesin receptor subtype 3 (BRS-3) antagonist (IC50 = 4.8 μM). ML-18 inhibits lung cancer growth. ML-18 inhibited the proliferation of lung cancer cells.
• 1-Methylimidazolidine-2,4,5-trione (Catalog# : 1781501, Cas# : 3659-97-0)1-MethyliMidazolidine-2,4,5-Trione 
• MK-1064 (Catalog# : 16123054, Cas# : 1207253-08-4)MK-1064 is a potent, selective and orally active Orexin OX2 Receptor Antagonist for potential treatment of insomnia.
• MI-503 (Catalog# : 178908, Cas# : 1857417-13-0)MI-503 is a potent and selective Menin-MLL inhibitor with IC50 of 14.7 nM. It shows pronounced growth suppressive activity in a panel of human MLL leukemia cell lines(GI50 at 250
• Merestinib (LY2801653) (Catalog# : 178905, Cas# : 1206799-15-6)Merestinib, also known as LY2801653, is a n orally available, small molecule inhibitor of the proto-oncogene c-Met (mesenchymal-epithelial transition, also known as hepatocyte gr
• Miglustat hydrochloride (Catalog# : 2017824, Cas# : 210110-90-0) Miglustat, also known as OGT 918, is a drug developed by Actelion and is used primarily to treat Type I Gaucher disease (GD1). 
• MK-0812 (Catalog# : 2017080111, Cas# : 624733-88-6)MK-0812 is a potent and selective CCR2 antagonist. Chemokine (C-C motif) receptor 2 (CCR2) is central for the migration of monocytes into inflamed tissues. 
• MONASCIN (Catalog# : 201708015, Cas# : 21516-68-7)It is a potent inhibitor of car inogenesis measured against chemical- or UV-initiated, phorbol-promoted mouse skin tumours. 
• Mephenytoin (Catalog# : 174161, Cas# : 50-12-4)Mephenytoin(CAS 50-12-4) is a hydantoin, used as an anticonvulsant.Mephenytoin(CAS 50-12-4)is a hydantoin-derivative anticonvulsant used to control various partial seizures. It i
• MT-DADMe-ImmA (Catalog# : 703301, Cas# : 653592-04-2)Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-pm inhibitor of human 5-methylthioadenosine phosphorylase (MTAP).  Treatment of cultured cells with MT-DADMe-ImmA and MTA i
• MI-463 (Catalog# : 17031006, Cas# : 1628317-18-9)MI-463 is a potent inhibitor of Menin-MLL interaction with an IC50 value of 15.3 nM. 
• ML-098 (Catalog# : 17030910, Cas# : 878978-76-8)ML-098, also known as CID-7345532, is an activator of the GTP-binding protein Rab7 (EC50 = 77.6 nM). ML098 (CID-7345532) functions by increasing the affinity of the GTPases for g
• ML-265 (Catalog# : 17030804, Cas# : 1221186-53-3)ML265 is a potent PKM2 activator induces tetramerization and reduces tumor formation and size in a mouse xenograft model. Cancer cells have altered metabolic processes compared t
• MN-64 (Catalog# : 17030717, Cas# : 92831-11-3)MN-64 is a potent and selective inhibitor of Tankyrase 1 and 2 (IC50 = 6 and 72 nM, respectively). MN-64 blocks Wnt signaling in HEK293 cells containing a Wnt pathway reporter sy
• ML241 (Catalog# : 17030714, Cas# : 1346528-06-0)ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase with IC(50) values of 100 nM. ML241 inhibits degradation of a p97-dependent but not a p97-indep
• ML348 (Catalog# : 17030712, Cas# : 899713-86-1)ML348, also known as CID 3238952; SID 160654487, is a reversible LYPLA1 inhibitor with an IC50 value of 210 nM. Multiple oncogenes, including HRAS and SRC, require palmitoylation
• Mavoglurant (Catalog# : 17030612, Cas# : 543906-09-8)Mavoglurant, aslo known as AFQ056, is an experimental drug candidate for the treatment of fragile X syndrome. Mavoglurant exerts its effect as an antagonist of the metabotropic g
• MMAF (Monomethyl auristatin F) (Catalog# : 17030611, Cas# : 745017-94-1)Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD
• Merimepodib (Catalog# : 17030308, Cas# : 198821-22-6)Merimepodib, also known as VX-497, is orally bioavailable IMPDH inhibitor, which inhibits the proliferation of primary human, mouse, rat, and dog lymphocytes at concentrations of
• ML-264 (Catalog# : 17030302, Cas# : 1550008-55-3)ML-264 is a Krppel-like factor 5 (KLF5) inhibitor That Potently Inhibits Growth of Colorectal Cancer. ML264 is highly active (IC50 = 29 nM is a cell-based assay for proliferation
• MK-8245 (Catalog# : 17030109, Cas# : 1030612-90-8)MK-8245 is a potent, liver-targeted SCD inhibitor with preclinical antidiabetic and antidyslipidemic efficacy with a significantly improved therapeutic window. MK-8245 was believ
• MLN-1117 (Catalog# : 17030101, Cas# : 1268454-23-4)Serabelisib (also known as MLN1117, INK1117, and TAK-117) is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha isoform with potential antineo
• ML-281 (Catalog# : 17022811, Cas# : 1404437-62-2)ML-281 is a potent ans selective STK33 inhibitor (IC50 = 14 nM). ML281 showed low nanomolar inhibition of purified recombinant STK33 and a distinct selectivity profile as compare
• Maraviroc (Catalog# : 17022804, Cas# : 376348-65-1)Maraviroc (UK-427857; Selzentry; Celsentri) is a selective CCR5 antagonist (IC50= 6.4 nM); displays potent anti-HIV-1 activity. Maraviroc (UK-427857; Selzentry; Celsentri) prev
• MMAE (Monomethyl auristatin E) (Catalog# : 17022403, Cas# : 474645-27-7)MMAE, also known as Monomethyl auristatin E, is a synthetic antineoplastic agent. Because of its toxicity, it cannot be used as a drug itself; instead, it is linked to a monoclon