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MAPK
Membrane Transporter/Ion Channel
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index M
MDK19922
(Catalog# : 1791512, Cas# :
132819-92-2
)
MDK19922, also known as NOD-IN-1 or Compound 4, is a Potent inhibitor of nucleotide-b
Mozavaptan free base
(Catalog# : 179154, Cas# :
137975-06-5
)
Mozavaptan, also known as OPC 31260, is a vasopressin receptor antagonist marketed by
ML-141
(Catalog# : 179152, Cas# :
71203-35-5
)
ML-141, also known as CID2950007, is a Cdc42 inhibitor (EC50 = 2.1 μM).
MDK30165
(Catalog# : 179138, Cas# :
2060530-16-5
)
MDK30165, also known as K-Ras(G12C) Inhibitor 6.
MMAD
(Catalog# : 20179132, Cas# :
203849-91-6
)
MMAD, also known as Monomethyl auristatin D, is a highly potent Tubulin inhibitor. MM
ML-385
(Catalog# : 179119, Cas# :
846557-71-9
)
ML-385 is a potent and selective NRF2 inhibitor (Nrf2; IC50 = 1.9 μM) . ML-385 selec
ML-277
(Catalog# : 179115, Cas# :
516480-79-8
)
ML-277, also known as Chk2 Inhibitor II, is a Chk2 (checkpoint kinase 2) inhibitor. B
MDK35833
(Catalog# : 179114, Cas# :
1016535-83-3
)
MDK35833, also known as Oct3/4-inducer-1, is a potent Oct3/4-inducer. MDK35833 can pr
ML241 HCl
(Catalog# : 179111, Cas# :
2070015-13-1
)
ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase wi
ML364
(Catalog# : 179833, Cas# :
1991986-30-1
)
ML364 is a small molecule inhibitor of the deubiquitinase USP2 with potential antican
Mitoxantrone HCl
(Catalog# : 179827, Cas# :
70476-82-3
)
Mitoxantrone hydrochloride is the hydrochloride salt of an anthracenedione antibiotic
ML311
(Catalog# : 179826, Cas# :
315698-17-0
)
ML311, also known as EU-5346, is a potent and selective inhibitor of the Protein-Prot
ML-18
(Catalog# : 179810, Cas# :
1422269-30-4
)
ML18 is Bombesin receptor subtype 3 (BRS-3) antagonist (IC50 = 4.8 μM). ML-18 inhibi
1-Methylimidazolidine-2,4,5-trione
(Catalog# : 1781501, Cas# :
3659-97-0
)
1-MethyliMidazolidine-2,4,5-Trione
MK-1064
(Catalog# : 16123054, Cas# :
1207253-08-4
)
MK-1064 is a potent, selective and orally active Orexin OX2 Receptor Antagonist for p
MI-503
(Catalog# : 178908, Cas# :
1857417-13-0
)
MI-503 is a potent and selective Menin-MLL inhibitor with IC50 of 14.7 nM. It shows p
Merestinib (LY2801653)
(Catalog# : 178905, Cas# :
1206799-15-6
)
Merestinib, also known as LY2801653, is a n orally available, small molecule inhibito
Miglustat hydrochloride
(Catalog# : 2017824, Cas# :
210110-90-0
)
Miglustat, also known as OGT 918, is a drug developed by Actelion and is used prima
MK-0812
(Catalog# : 2017080111, Cas# :
624733-88-6
)
MK-0812 is a potent and selective CCR2 antagonist. Chemokine (C-C motif) receptor 2 (
MONASCIN
(Catalog# : 201708015, Cas# :
21516-68-7
)
It is a potent inhibitor of car inogenesis measured against chemical- or UV-initiated
Mephenytoin
(Catalog# : 174161, Cas# :
50-12-4
)
Mephenytoin(CAS 50-12-4) is a hydantoin, used as an anticonvulsant.Mephenytoin(CAS 50
MT-DADMe-ImmA
(Catalog# : 703301, Cas# :
653592-04-2
)
Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-pm inhibitor of human 5-methyl
MI-463
(Catalog# : 17031006, Cas# :
1628317-18-9
)
MI-463 is a potent inhibitor of Menin-MLL interaction with an IC50 value of 15.3 nM
ML-098
(Catalog# : 17030910, Cas# :
878978-76-8
)
ML-098, also known as CID-7345532, is an activator of the GTP-binding protein Rab7 (E
ML-265
(Catalog# : 17030804, Cas# :
1221186-53-3
)
ML265 is a potent PKM2 activator induces tetramerization and reduces tumor formation
MN-64
(Catalog# : 17030717, Cas# :
92831-11-3
)
MN-64 is a potent and selective inhibitor of Tankyrase 1 and 2 (IC50 = 6 and 72 nM, r
ML241
(Catalog# : 17030714, Cas# :
1346528-06-0
)
ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase wi
ML348
(Catalog# : 17030712, Cas# :
899713-86-1
)
ML348, also known as CID 3238952; SID 160654487, is a reversible LYPLA1 inhibitor wit
MMAF (Monomethyl auristatin F)
(Catalog# : 17030611, Cas# :
745017-94-1
)
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of som
Merimepodib
(Catalog# : 17030308, Cas# :
198821-22-6
)
Merimepodib, also known as VX-497, is orally bioavailable IMPDH inhibitor, which inhi
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-
Atuzabrutinib
(Catalog# : 25145, Cas# :
1581714-49-9
)
Atuzabrutinib, also known as PRN 473, is a Bruton's tyrosine kinase inhibitor.
Andamertinib
(Catalog# : 25144, Cas# :
2254145-43-0
)
Andamertinib is an epidermal growth factor receptor tyrosine kinase inhibitor. It is
MEN-1703
(Catalog# : 25143, Cas# :
2769008-22-0
)