Welcome to Sun-shine chemical
+86-17702719238 sales@sun-shinechem.com

ML-281

Catalog No: 17022811
CAS Number: 1404437-62-2
Purity: 98% 

ML-281 is a potent ans selective STK33 inhibitor (IC50 = 14 nM). ML281 showed low nanomolar inhibition of purified recombinant STK33 and a distinct selectivity profile as compared to other STK33 inhibitors. ML281 is a valuable addition to small-molecule probes of STK33. v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most mutated oncogene, and KRAS mutations have been found in up to 20% of all human tumors. STK33 was selectively toxic to KRAS-dependent cancer cell lines, suggesting that small-molecule inhibitors of STK33 might selectively target KRAS-dependent cancers. 

For research use only. We do not sell to patients.

Chemical Information

NameML-281
Iupac Chemical NameML-281 
SynonymsML-281; ML-281; ML281 
Molecular FormulaC22H19N3O2S 
Molecular Weight389.473 
InChiKey
InChi
CAS Number1404437-62-2
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
Request Bulk Quote Download MSDS Tel : +86-177 0271 9238   Email : sales@sun-shinechem.com
Formulationoff-white solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

17022811 - ML-281 | CAS 1404437-62-2

Quick Order

Change