ML348
Catalog No: 17030712
CAS Number: 899713-86-1
Purity: 98%
ML348, also known as CID 3238952; SID 160654487, is a reversible LYPLA1 inhibitor with an IC50 value of 210 nM. Multiple oncogenes, including HRAS and SRC, require palmitoylation for malignant transformation. Lysophospholipase 1 (LYPLA1) has been identified as a candidate protein palmitoyl thioesterase responsible for HRAS depalmitoylation in mammalian cells.
For research use only. We do not sell to patients.
Chemical Information
| Name | ML348 |
|---|---|
| Iupac Chemical Name | N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide |
| Synonyms | ML348; ML-348; ML 348; CID 3238952; SID 160654487 |
| Molecular Formula | C18H17ClF3N3O3 |
| Molecular Weight | 415.7972 |
| Smile | ClC1=C(C=C(C=C1)C(F)(F)F)NC(CN1CCN(CC1)C(=O)C=1OC=CC1)=O |
| InChiKey | OXKNHBBDOIMFFQ-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H17ClF3N3O3/c19-13-4-3-12(18(20,21)22)10-14(13)23-16(26)11-24-5-7-25(8-6-24)17(27)15-2-1-9-28-15/h1-4,9-10H,5-8,11H2,(H,23,26) |
| CAS Number | 899713-86-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
