MS049
Catalog No: 17021313
CAS Number: 1502816-23-0
Purity: 98%
MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively.
MS049 does not inhibit any of the methyltransferases at 50 M or demethylases at 10 M and does not display appreciable binding to any of the methyllysine/methylarginine reader proteins using the DSF assay at 200 M. MS049 demonstrated excellent selectivity over a broad range of epigenetic and nonepigenetic targets. In cellular assays, MS049 potently inhibits the methyltransferase activity of PRMT4 and PRMT6 and reduces levels of Med12me2a and H3R2me2a in HEK293 cells.
For research use only. We do not sell to patients.
Chemical Information
| Name | MS049 |
|---|---|
| Iupac Chemical Name | MS049 |
| Synonyms | N/A |
| Molecular Formula | C15H26Cl2N2O |
| Molecular Weight | 321.29 |
| InChiKey | |
| InChi | |
| CAS Number | 1502816-23-0 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
