MN-64
Catalog No: 17030717
CAS Number: 92831-11-3
Purity: 98%
MN-64 is a potent and selective inhibitor of Tankyrase 1 and 2 (IC50 = 6 and 72 nM, respectively). MN-64 blocks Wnt signaling in HEK293 cells containing a Wnt pathway reporter system. Tankyrases are ADP-ribosyltransferases that play key roles in various cellular pathways, including the regulation of cell proliferation, and thus, they are promising drug targets for the treatment of cancer.
For research use only. We do not sell to patients.
Chemical Information
| Name | MN-64 |
|---|---|
| Iupac Chemical Name | 2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one |
| Synonyms | MN-64; MN 64; MN64 |
| Molecular Formula | C18H16O2 |
| Molecular Weight | 264.324 |
| Smile | CC(C)C1=CC=C(C=C1)C=1OC2=C(C(C1)=O)C=CC=C2 |
| InChiKey | PYTOHIUBXSJKQH-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H16O2/c1-12(2)13-7-9-14(10-8-13)18-11-16(19)15-5-3-4-6-17(15)20-18/h3-12H,1-2H3 |
| CAS Number | 92831-11-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
