ML241
Catalog No: 17030714
CAS Number: 1346528-06-0
Purity: 98%
ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase with IC(50) values of 100 nM. ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the chemotherapy of cancer, and provide a rationale for developing pathway-specific p97 inhibitors.
For research use only. We do not sell to patients.
Chemical Information
| Name | ML241 |
|---|---|
| Iupac Chemical Name | 2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-5,6,7,8-tetrahydroquinazolin-4-amine |
| Synonyms | ML241; ML-241; ML 241 |
| Molecular Formula | C23H24N4O |
| Molecular Weight | 372.46286 |
| Smile | O1C2=C(N(CC1)C1=NC=3CCCCC3C(=N1)NCC1=CC=CC=C1)C=CC=C2 |
| InChiKey | RMZPVQQGYVSLAP-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H24N4O/c1-2-8-17(9-3-1)16-24-22-18-10-4-5-11-19(18)25-23(26-22)27-14-15-28-21-13-7-6-12-20(21)27/h1-3,6-9,12-13H,4-5,10-11,14-16H2,(H,24,25,26) |
| CAS Number | 1346528-06-0 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
