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PI3K/Akt/mTOR
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MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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Cas Index 2
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Cas Index 2
2107880-93-1 | ethyl 2-(2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetate
(Catalog# : 2062030)
2216712-66-0 | Elexacaftor
(Catalog# : 2052801)
Elexacaftor, also known as VX-445 and WHO 11180, is a next-generation cystic fibrosis
2137030-98-7 | Ensartinib hydrochloride
(Catalog# : 1843212)
Ensartinib is an orally available small molecule inhibitor of the receptor tyrosine k
289483-69-8 | E7820
(Catalog# : 1812293)
E7820 is a small molecule and aromatic sulfonamide derivative with potential antiangi
2098546-05-3 | EBI-2511
(Catalog# : 1810165)
EBI-2511 is a Highly Potent and Orally Active EZH2 Inhibitor for the Treatment of Non
229476-53-3 | EBE-A22
(Catalog# : 179831)
EBE-A22 is a derivative of PD 153035. EBE-A22, has no effect on EGF-R TK but maintain
2083627-02-3 | EED226
(Catalog# : 178311)
EED226 is a potent, selective, and orally bioavailable EED inhibitor. induces robust
251303-04-5 | Ertiprotafib
(Catalog# : 16122942)
Ertiprotafib, also known as PTP-112, is a Protein Tyrosine Phosphatase 1B Inhibitor (
269055-15-4 | Etravirine (TMC125)
(Catalog# : 16122767)
Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used
254750-02-2 | Emricasan
(Catalog# : 16071024)
Emricasan (IDN-6556, PF-03491390) is a potent irreversible pan-caspaseinhibitor with
223488-57-1 | Evatanepag
(Catalog# : 011922)
Coming soon!
226954-04-7 | Emapunil
(Catalog# : 011303)
Emapunil is a translocator protein [TSPO (18 kDa)] ligand.
202409-33-4 | Etoricoxib
(Catalog# : 82709)
Etoricoxib selectively inhibited COX-2 in human whole blood assays in vitro, with an
24922-02-9 | Ethyl 3-cyclopropyl-3-oxopropanoate
(Catalog# : 81302)
Related API & intermediates:Cas#147526-32-7 Pitavastatin CalciumCas# 32249-35-7 M
209783-80-2 | Entinostat
(Catalog# : 52607)
Entinostat (MS-275; SNDX 275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 M a
2417298-29-2 | FC-116
(Catalog# : 20569)
FC-116 is a Tubulin inhibitor that effectively inhibits tumor growth in mice.
2671128-05-3 | FHD-286
(Catalog# : 20471)
FHD-286 is an oral, small-molecule, selective, allosteric inhibitor of BRG1 and BRM i
2093305-05-4 | Fosgonimeton (ATH-1017)
(Catalog# : 1711225)
Fosgonimeton (ATH-1017) is a small molecule which enhance the activity of hepatocyte
2226521-65-7 | FM-381
(Catalog# : 20122201)
FM-381 is a Chemical Probe For JAK3 and JAK3 specific reversible covalent inhibitor.
2243736-45-8 | FB23-2
(Catalog# : 207102)
FB23-2 is a potent FTO inhibitor. FB23-2 demonstrated the potent inhibitory impact in
251577-09-0 | FTI-2148
(Catalog# : 111897)
FTI-2148 is a potent farnesyltransferase inhibitor with potential antitumor activity.
215589-63-2 | FR-190809
(Catalog# : 193253)
FR-190809 is a potent, nonadrenotoxic, orally efficacious ACAT inhibitor.
211735-76-1 | Farampator
(Catalog# : 179156)
Farampator, also known as Org-24448; CX-691, is an AMPA receptor positive allosteric
2698-69-3 | 4-FORMYL-2-METHOXY-3-NITROPHENYL ACETATE
(Catalog# : 178225)
4-FORMYL-2-METHOXY-3-NITROPHENYL ACETATE
223387-75-5 | FG-2216
(Catalog# : 16122812)
FG-2216, also known as YM311, is orally bioavailable HIF-prolyl hydroxylase inhibitor
21679-14-1 | Fludarabine
(Catalog# : 021901)
Fludarabine, a DNA synthesis inhibitor, is a chemotherapy drug used in the treatment
23110-15-8 | Fumagillin
(Catalog# : 122910)
Fumagillin is a complex biomolecule and used as an antimicrobial agent.
2369-11-1 | 5-Fluoro-2-nitroaniline
(Catalog# : 110216)
Coming soon!
25451-15-4 | Felbamate
(Catalog# : 52752)
Felbamate (FBM) is a potent nonsedative anticonvulsant whose clinical effect may be r
2648450-42-2 | GNE-7883
(Catalog# : 20589)
GNE-7883 is a pan-TEAD inhibitor.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
2739866-40-9 | NVL-655 ( ALK-IN-27 )
(Catalog# : 24003)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add