DS68591889
Catalog No: 25158
CAS Number: 2488609-21-6
Purity: ≧98.0%
DS68591889 (PTDSS1i) 特异性抑制 PTDSS1，而 PTDSS1 可催化丝氨酸掺入 PC。
For research use only. We do not sell to patients.
Chemical Information
| Name | DS68591889 |
|---|---|
| Iupac Chemical Name | 7-(5-(2,2-difluoropropyl)-4-(4-(3-methyl-4-(trifluoromethoxy)phenoxy)phenyl)-6-oxo-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)benzo[d]oxazol-2(3H)-one |
| Synonyms | DS 68591889 ; DS 68591889 ; DS-68591889 |
| Molecular Formula | C29H21F5N4O5 |
| Molecular Weight | 600.50 |
| Smile | O=C1OC2=C(C3=NNC4=C3C(C5=CC=C(OC6=CC=C(OC(F)(F)F)C(C)=C6)C=C5)N(CC(F)(F)C)C4=O)C=CC=C2N1 |
| InChiKey | RCVCNESVDVTQMU-UHFFFAOYSA-N |
| InChi | InChI=1S/C29H21F5N4O5/c1-14-12-17(10-11-20(14)43-29(32,33)34)41-16-8-6-15(7-9-16)24-21-22(18-4-3-5-19-25(18)42-27(40)35-19)36-37-23(21)26(39)38(24)13-28(2,30)31/h3-12,24H,13H2,1-2H3,(H,35,40)(H,36,37) |
| CAS Number | 2488609-21-6 |
| Related CAS | 2488609-21-6 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色固体 |
|---|---|
| Purity | ≧98.0% |
| Storage | 0-4℃，可保存几天到几周；-20℃，可保存 几个月。 |
| Solubility | 溶于DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | 作为非危险化学品在环境温度下装运。这种产品在正常运输和海关工作期间可以稳定几周. |
| HS Code | 2934200090 |
Coming soon.
| Targets | PTDSS1 Inhibitor |
|---|---|
| Mechanism | DS68591889 is a selective and orally active phosphatidylserine synthase 1 (PTDSS1) inhibitor. DS68591889 has no inhibitory activity against PTDSS2. DS68591889 induces the phospholipid imbalance in a wide range of cancer cells. DS68591889 negatively regulates B cell receptor (BCR)-induced Ca2+ signaling and subsequent apoptotic cell death. DS68591889 can be used for the cancer research, such as B cell lymphoma. |
| Cell study | |
| Animal study | |
| Clinical study |
Chemical Structure
