Dencatistat
Catalog No: 25177
CAS Number: 2377000-84-3
Purity: ≧98.0%
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosphate synthase 1 (CTPS1), with potential antineoplastic activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | Dencatistat |
|---|---|
| Iupac Chemical Name | 4-(2-(cyclopropanesulfonamido)pyrimidin-4-yl)-N-(5-(6-ethoxypyrazin-2-yl)pyridin-2-yl)tetrahydro-2H-pyran-4-carboxamide |
| Synonyms | Dencatistat ; CTPS1-IN-2 ; STP938 |
| Molecular Formula | C24H27N7O5S |
| Molecular Weight | 525.58 |
| Smile | O=C(C1(C2=NC(NS(=O)(C3CC3)=O)=NC=C2)CCOCC1)NC4=NC=C(C5=NC(OCC)=CN=C5)C=C4 |
| InChiKey | WVCJRTCHVUNXST-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H27N7O5S/c1-2-36-21-15-25-14-18(28-21)16-3-6-20(27-13-16)30-22(32)24(8-11-35-12-9-24)19-7-10-26-23(29-19)31-37(33,34)17-4-5-17/h3,6-7,10,13-15,17H,2,4-5,8-9,11-12H2,1H3,(H,26,29,31)(H,27,30,32) |
| CAS Number | 2377000-84-3 |
| Related CAS | 2377000-84-3 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | White to off-white (Solid) |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : 12.5mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | CTPS1 inhibitor |
|---|---|
| Mechanism | Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosphate synthase 1 (CTPS1), with potential antineoplastic activity. |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
