202475-60-3 | JANEX-1 (Catalog# : 52220)Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (IC50 = 78 M); has no effect on JAK1, JAK2, or Zap/Syk or SRC tyrosine kinases
228559-41-9 | Ki8751 (Catalog# : 17022703)Ki8751 is a potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC50 = 0.9 nM). Displays some inhibitory activity towards c-Kit, PDGFR and FGFR-2 (IC50 values range from 40
286370-15-8 | KRN 633 (Catalog# : 51912)KRN 633 is an ATP-competitive inhibitor ofVEGFR1/2/3withIC50of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-/ and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Me
245075-84-7 | LR-90 (Catalog# : 19364)LR-90 is an advanced glycation end product (AGE) inhibitor, inhibits inflammatory responses in human monocytes. LR-90 is also used in the research of diabetic animal model.
2222755-14-6 | LOXO-292 (Catalog# : 192195)LOXO-292 (ARRY-192) is an oral and selective investigational drug in clinical development for the treatment of patients with cancers that harbor abnormalities in the rearranged d
2097002-61-2 | LOXO-195 (Catalog# : 185212)LOXO-195 is a potent and selective TRK inhibitor capable of addressing potential mechanisms of acquired resistance that may emerge in patients receiving larotrectinib (LOXO-101)
264622-53-9 | MRS1706 (Catalog# : 19131)MRS1706 is a selective adenosine A2B receptor inverse agonist with Ki values of 1.39, 157, 112, and 230 nM for human A2B, A1, A2A, and A3 receptors, respectively.
2070015-10-8 | ML204 HCl (Catalog# : 18422)ML204 is a novel and potential TRPC4 Channel inhibitor.ML204 represents an excellent novel tool for investigation of TRPC4 channel function and may facilitate the development of
203849-91-6 | MMAD (Catalog# : 20179132)MMAD, also known as Monomethyl auristatin D, is a highly potent Tubulin inhibitor. MMAD is one of the auristatins, which are used as the drugs of antibody drug conjugates(ADCs).