223387-75-5 | FG-2216 (Catalog# : 16122812)FG-2216, also known as YM311, is orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant and reversible Epo induction in vivo. FG-2216 showed the abilit
278779-30-9 | GW4064 (Catalog# : 16071018)GW-4064 is a selective agonist of FXR (EC50 = 15 nM).2 It displays no activity at other nuclear receptors, including the retinoic acid receptor, at concentrations up to 1 M. GW-4
22978-25-2 | GW9662 (Catalog# : 52304)GW9662 is a selective PPAR antagonist forPPARwithIC50of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPAR versus PPAR and PPAR.
2158197-70-5 | HS-1371 (Catalog# : 192223)HS-1371 is a novel kinase inhibitor of RIP3-mediated necroptosis. HS-1371 directly binds to RIP3 in an ATP-competitive and time-independent manner, providing a mechanism of action.
2074607-48-8 | IWP-O1 (Catalog# : 186222)IWP-O1 is highly potent Porcn inhibitor, is essential for the secretion of Wnt proteins which contribute to embryonic development, tissue regeneration, and tumorigenesis.
23146-22-7 | IQ-1S (Catalog# : 16123021)IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S is highly specific for JNK and that its neutral form
259869-55-1 | JWH-133 (Catalog# : 6111109)JWH 133 is a potent CB2 selective agonist with Ki of 3.4 nM, 200-fold selective over CB1 receptors. JWH-133 inhibits IL-12p40 production and enhances IL-10 release by activated