Cadefrecitinib (GLPG-3667)
Catalog No: 20509
CAS Number: 2308520-97-8
Purity: ≧98.0%
Cadefrecitinib (GLPG-3667) is an oral, small molecule inhibitor of the TYK2 kinase in phase II clinical development as a treatment for dermatomyositis and active systemic lupus erythematosus.
For research use only. We do not sell to patients.
Chemical Information
| Name | Cadefrecitinib (GLPG-3667) |
|---|---|
| Iupac Chemical Name | 4-methyl-5-((3-methyl-7-((6-morpholinopyridazin-3-yl)amino)-3H-imidazo[4,5-b]pyridin-5-yl)oxy)picolinonitrile |
| Synonyms | GLPG3667 ; GLPG-3667 ; GLPG 3667 ;Cadefrecitinib |
| Molecular Formula | C22H21N9O2 |
| Molecular Weight | 443.47 |
| Smile | N#CC1=NC=C(OC2=CC(NC3=NN=C(N4CCOCC4)C=C3)=C5C(N(C)C=N5)=N2)C(C)=C1 |
| InChiKey | GXELZXDURVDKHP-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H21N9O2/c1-14-9-15(11-23)24-12-17(14)33-20-10-16(21-22(27-20)30(2)13-25-21)26-18-3-4-19(29-28-18)31-5-7-32-8-6-31/h3-4,9-10,12-13H,5-8H2,1-2H3,(H,26,27,28) |
| CAS Number | 2308520-97-8 |
| Related CAS | 2308520-97-8 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
