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CHS-828

Catalog No: 100904
CAS Number: 200484-11-3
Purity: 98% 

CHS-828, also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting the nuclear factor-kappaB translocation but unlikely through down-regulation of proteasome. CHS 828 has shown promising anticancer activity in experimental tumor models and primary cultures of cancer cells from patients. 

For research use only. We do not sell to patients.

Chemical Information

NameCHS-828
Iupac Chemical Name(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine 
SynonymsCHS 828; CHS828; GMX-1778; GMX1778; GMX 1778 
Molecular FormulaC19H22ClN5O 
Molecular Weight371.86 
SmileClC1=CC=C(OCCCCCCN/C(=N\C#N)/NC2=CC=NC=C2)C=C1
InChiKeyBOIPLTNGIAPDBY-UHFFFAOYSA-N
InChiInChI=1S/C19H22ClN5O/c20-16-5-7-18(8-6-16)26-14-4-2-1-3-11-23-19(24-15-21)25-17-9-12-22-13-10-17/h5-10,12-13H,1-4,11,14H2,(H2,22,23,24,25)
CAS Number200484-11-3
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

100904 - CHS-828 | CAS 200484-11-3

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