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PF-04691502

Catalog No.: 123020
Cas No.: 1013101-36-4
Purity : 98% 
123020 - PF-04691502 | CAS 1013101-36-4

Catalog number : 123020

CAS number : 1013101-36-4

分子式 : C22H27N5O4 

分子量 : 425.481 

Iupac 化学名称 : 2-amino-8-[4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7-one 

Smile : CC1=C2C=C(C(=O)N(C2=NC(=N1)N)C3CCC(CC3)OCCO)C4=CN=C(C=C4)OC

InChiKey : XDLYKKIQACFMJG-UHFFFAOYSA-N

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同义词PF 04691502; PF04691502 
英文同义词PF 04691502; PF04691502 
分子式C22H27N5O4 
分子量425.481 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=C2C=C(C(=O)N(C2=NC(=N1)N)C3CCC(CC3)OCCO)C4=CN=C(C=C4)OC
InChiKeyXDLYKKIQACFMJG-UHFFFAOYSA-N
InChiInChI=1S/C22H27N5O4/c1-13-17-11-18(14-3-8-19(30-2)24-12-14)21(29)27(20(17)26-22(23)25-13)15-4-6-16(7-5-15)31-10-9-28/h3,8,11-12,15-16,28H,4-7,9-10H2,1-2H3,(H2,23,25,26)
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PF-04691502 is an ATP-competitive PI3K(///)/mTOR dual inhibitor with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. 

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