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PKC412

Catalog No.: 123013
Cas No.: 120685-11-2
Purity : 98% 
123013 - PKC412 | CAS 120685-11-2

Catalog number : 123013

CAS number : 120685-11-2

分子式 : C35H30N4O4 

分子量 : 570.637 

Iupac 化学名称 : PKC 412,[9S-(9S,10R,11R,13R)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl)-N-methylbenzamide  

Smile : CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC

InChiKey : BMGQWWVMWDBQGC-UHFFFAOYSA-N

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同义词CGP41231; CGP41251; Midostaurin; PKC 412; PKC-412; CGP 41231; CGP 41251 
英文同义词CGP41231; CGP41251; Midostaurin; PKC 412; PKC-412; CGP 41231; CGP 41251 
分子式C35H30N4O4 
分子量570.637 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
InChiKeyBMGQWWVMWDBQGC-UHFFFAOYSA-N
InChiInChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)
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PKC412 is a broad spectrum protein kinase inhibitor; inhibits conventional PKC isoforms (, , ), PDFR, VEGFR2, Syk, PKC, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. 

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