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PF-04447943

Catalog No.: 122515
Cas No.: 1082744-20-4
Purity : 98% 
122515 - PF-04447943 | CAS 1082744-20-4

Catalog number : 122515

CAS number : 1082744-20-4

分子式 : C20H25N7O2 

分子量 : 395.458 

Iupac 化学名称 : 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(oxan-4-yl)-2H-pyrazolo[3,4-d]pyrimidin-4-one 

Smile : CC1CN(CC1C2=NC(=O)C3=CNN(C3=N2)C4CCOCC4)CC5=NC=CC=N5

InChiKey : ACXPOEVOYNJCHF-UHFFFAOYSA-N

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同义词PF 04447943; PF04447943 
英文同义词PF 04447943; PF04447943 
分子式C20H25N7O2 
分子量395.458 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1CN(CC1C2=NC(=O)C3=CNN(C3=N2)C4CCOCC4)CC5=NC=CC=N5
InChiKeyACXPOEVOYNJCHF-UHFFFAOYSA-N
InChiInChI=1S/C20H25N7O2/c1-13-10-26(12-17-21-5-2-6-22-17)11-16(13)18-24-19-15(20(28)25-18)9-23-27(19)14-3-7-29-8-4-14/h2,5-6,9,13-14,16,23H,3-4,7-8,10-12H2,1H3
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PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor (Ki of 2.8, 4.5 and 18 nM) for human, rhesus and rat recombinant PDE9 respectively and high selectivity for PDE9 versus PDEs1-8 and 10-11. 

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